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  3. Tle4 - transducin-like enhancer of split 4 Gene

Tle4 - transducin-like enhancer of split 4 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Bce1; Grg4; Bce-1; grg-4; ESTM13; ESTM14; 5730411M05Rik

基因 ID: 21888 | 基因类型: protein coding

关于 Tle4

功能概要

Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription corepressor activity. Involved in negative regulation of transcription, DNA-templated. Acts upstream of or within Wnt signaling pathway; cellular response to leukemia inhibitory factor; and negative regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; embryo mesenchyme; genitourinary system; and peripheral nervous system ganglion. Orthologous to human TLE4 (TLE family member 4, transcriptional corepressor). [provided by Alliance of Genome Resources, Apr 2022]

Tle4 基因产物(4)

mRNA Protein Name
NM_001302947.2 NP_001289876.1 transducin-like enhancer protein 4 isoform 1
NM_001302950.2 NP_001289879.1 transducin-like enhancer protein 4 isoform 3
NM_001302951.2 NP_001289880.1 transducin-like enhancer protein 4 isoform 4
NM_011600.4 NP_035730.2 transducin-like enhancer protein 4 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA-binding transcription factor binding IPI
IPI: 通过物理相互作用推断
21317240 MGI
enables chromatin binding IDA
IDA: 通过直接分析推断
16002402 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12050133 MGI
enables transcription corepressor activity IDA
IDA: 通过直接分析推断
12050133 MGI
enables transcription corepressor activity IGI
IGI: 通过遗传相互作用推断
15729346 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within Wnt signaling pathway IDA
IDA: 通过直接分析推断
15105370 MGI
acts upstream of or within cellular response to leukemia inhibitory factor IEP
IEP: 通过表达模式推断
20439489 MGI
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
12050133 MGI
involved in negative regulation of DNA-templated transcription IDA
IDA: 通过直接分析推断
21317240 MGI
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
16002402 MGI
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
23371388 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
17060451 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

transducin-like enhancer protein 4

B lymphocyte gene 1

groucho-related protein 4

transducin-like enhancer of split 4, homolog of Drosophila E(spl)

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14566 TLE4 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21444 Tle4 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tle4 NCBI NCBI:7091
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