RSPH9 - radial spoke head component 9 Gene

中文名称：径向辐条头组件 9

种属: Homo sapiens

同用名: CILD12; C6orf206; MRPS18AL1

基因 ID: 221421 | 基因类型: protein coding

关于 RSPH9

Cytogenetic location: 6p21.1 Genomic coordinates (GRCh38): 6:43,645,036-43,672,600 (from NCBI)

This gene has 2 transcripts (splice variants), 208 orthologues and is associated with 2 phenotypes. Biased expression in testis (RPKM 11.2), lung (RPKM 1.7) and 1 other tissue.

功能概要

该基因编码的蛋白质被认为是活动纤毛和鞭毛中径向辐条头的组成部分。该基因的突变与原发性纤毛运动障碍 12 相关。可变剪接导致多种转录物变异。[RefSeq 提供，2010 年 7 月]

This gene encodes a protein thought to be a component of the radial spoke head in motile cilia and flagella. Mutations in this gene are associated with primary ciliary dyskinesia 12. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]

RSPH9 基因产物(2)

mRNA	Protein	Name
NM_001193341.2	NP_001180270.1	radial spoke head protein 9 homolog isoform 2
NM_152732.5	NP_689945.2	radial spoke head protein 9 homolog isoform 1

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in axoneme assembly	IMP IMP: 通过突变表型推断	19200523	GOA
involved in cilium movement	IMP IMP: 通过突变表型推断	19200523	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in 9+2 motile cilium	IDA IDA: 通过直接分析推断	26909801	GOA
located in axoneme	IDA IDA: 通过直接分析推断	26909801	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RSPH9 蛋白结构

Radial_spoke

0
100
200
276 a.a.

蛋白主名

其他名称

radial spoke head protein 9 homolog

radial spoke head 9 homolog

RSPH9 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	RSPH9	Q9H1X1	LONP2	Homo sapiens	Q86WA8	Anti Tag CoIP	33961781
种属内	RSPH9	Q9H1X1	LONP2	Homo sapiens	Q86WA8	TAP	27173435
种属内	RSPH9	Q9H1X1	LONP2	Homo sapiens	Q86WA8	Anti Tag CoIP	28514442
种属内	RSPH9	Q9H1X1	PNMA1	Homo sapiens	Q8ND90	Y2H Prey Pooling	25416956
种属内	RSPH9	Q9H1X1	PNMA1	Homo sapiens	Q8ND90	Validated Y2H	25416956
种属内	RSPH9	Q9H1X1	PNMA1	Homo sapiens	Q8ND90	Y2H Array	25416956

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Ciliary Dyskinesia, Primary, 12

CILD12	Primary Ciliary Dyskinesia 12
Primary Ciliary Dyskinesia 12 Without Situs Inversus	Ciliary Dyskinesia, Primary, 12, Without Situs Inversus
Ics12	Immotile Cilia Syndrome 12
Dyskinesia, Ciliary, Primary, Type 12

Primary Ciliary Dyskinesia

Immotile Cilia Syndrome	Kartagener Syndrome
Dextrocardia Bronchiectasis And Sinusitis	Pcd
Ciliary Motility Disorders	Ciliary Motility Disorder
Immotile Ciliary Syndrome	Ciliary Dyskinesia Primary
Ics	Polynesian Bronchiectasis
Dextrocardia-Bronchiectasis-Sinusitis Syndrome	Immotile Cilia Syndrome, Kartagener Type
Primary Ciliary Dyskinesia And Situs Inversus	Primary Ciliary Dyskinesia, Kartagener Type
Siewert Syndrome	Dyskinesia, Ciliary, Primary

Kartagener Syndrome

Kartagener'S Syndrome

Ciliary Dyskinesia, Primary, 10

Primary Ciliary Dyskinesia 10	CILD10
Primary Ciliary Dyskinesia 10 With Or Without Situs Inversus	Ciliary Dyskinesia, Primary, 10, With Or Without Situs Inversus
Ics10	Immotile Cilia Syndrome 10
Dyskinesia, Ciliary, Primary, 10

Situs Inversus

Situs Inversus Viscerum	Laterality Sequence
Complete Transposition	Siv

Bronchiectasis

Polynesian Bronchiectasis	Kartagener Syndrome
Bronchiectasis Nos

Ciliary Dyskinesia, Primary, 6

Primary Ciliary Dyskinesia 6	CILD6
Ics6	Immotile Cilia Syndrome 6
Dyskinesia, Ciliary, Primary, 6

Otorrhea

Discharging Ear

Ciliary Dyskinesia, Primary, 1

CILD1	Pcd
Primary Ciliary Dyskinesia 1	Kartagener Syndrome
Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	Immotile Cilia Syndrome
Ics	Polynesian Bronchiectasis
Primary Ciliary Dyskinesia 1 With Or Without Situs Inversus	Ics1
Immotile Cilia Syndrome 1	Primary Ciliary Dyskinesia
KTGS	Dextrocardia-Bronchiectasis-Sinusitis Syndrome
Immotile Cilia Syndrome Kartagener Type	Primary Ciliary Dyskinesia Kartagener Type
Siewert Syndrome	Immotile Cilia
Dyskinesia, Ciliary, Primary, Type 1	Ciliary Motility Disorders

Paranasal Sinus Disease

Paranasal Sinus Diseases

Disorder Of Nasal Sinus

Visceral Heterotaxy

Situs Ambiguus	Heterotaxia
Heterotaxy Syndrome	Heterotaxy
Lateralization Defect	Situs Ambiguous
Left Isomerism	Htx
Ivemark Syndrome	Right Isomerism
Situs Ambiguus Viscerum	Incomplete Situs Inversus
Partial Situs Inversus	Heterotaxy, Visceral
Asplenia Syndrome	Bilateral Left-Sidedness
Polysplenia Syndrome	Moller Syndrome

Middle Ear Disease

Middle Ear Anomaly

Disorder Of Middle Ear

Retinitis Pigmentosa

RP	Rod-Cone Dystrophy
Autosomal Recessive Retinitis Pigmentosa	Non-Syndromic Retinitis Pigmentosa
Pericentral Pigmentary Retinopathy	Pigmentary Retinopathy
Tapetoretinal Degeneration	Rcd
Retinitis Pigmentosa Autosomal Recessive	ARRP
Retinitis Pigmentosa, Autosomal Recessive	Retinitis Pigmentosa 1

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS12304	RSPH9 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	RSPH9	VGNC	VGNC:64795
Rattus norvegicus	RSPH9	RGD	RGD:1310693
Macaca mulatta	RSPH9	VGNC	VGNC:77072
Bos taurus	RSPH9	VGNC	VGNC:34187
Mus musculus	RSPH9	MGD	MGI:1922814
Canis familiaris	RSPH9	VGNC	VGNC:57231

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

RSPH9 - radial spoke head component 9 Gene

关于 RSPH9

功能概要

RSPH9 基因产物(2)

RSPH9 蛋白结构

RSPH9 蛋白互作信息

关联疾病

直系同源

热门区域

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RSPH9 - radial spoke head component 9 Gene

关于 RSPH9

功能概要

RSPH9 基因产物(2)

RSPH9 蛋白结构

RSPH9 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

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Z