2. Gene
  3. Tubb3 - tubulin, beta 3 class III Gene

Tubb3 - tubulin, beta 3 class III Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: M(beta)3; M(beta)6; 3200002H15Rik

基因 ID: 22152 | 基因类型: protein coding

关于 Tubb3

功能概要

Enables netrin receptor binding activity. Involved in axon guidance and netrin-activated signaling pathway. Located in several cellular components, including filopodium; growth cone; and lamellipodium. Is expressed in several structures, including alimentary system; cardiovascular system; embryo ectoderm; nervous system; and sensory organ. Used to study congenital fibrosis of the extraocular muscles. Human ortholog(s) of this gene implicated in complex cortical dysplasia with Other brain malformations 1 and congenital fibrosis of the extraocular muscles 3A. Orthologous to human TUBB3 (tubulin beta 3 class III). [provided by Alliance of Genome Resources, Apr 2022]

Tubb3 基因产物(1)

mRNA Protein Name
NM_023279.3 NP_075768.1 tubulin beta-3 chain
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables netrin receptor binding IPI
IPI: 通过物理相互作用推断
28483977 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17389232 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in axon guidance IMP
IMP: 通过突变表型推断
20074521 MGI
involved in netrin-activated signaling pathway IMP
IMP: 通过突变表型推断
28483977 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
15255972 MGI
located in cell periphery IDA
IDA: 通过直接分析推断
24378336 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
19036983 MGI
located in dendrite IDA
IDA: 通过直接分析推断
24464040 MGI
located in filopodium IDA
IDA: 通过直接分析推断
28483977 MGI
located in growth cone IDA
IDA: 通过直接分析推断
28483977 MGI
located in intracellular anatomical structure IDA
IDA: 通过直接分析推断
16892058 MGI
located in lamellipodium IDA
IDA: 通过直接分析推断
28483977 MGI
located in microtubule cytoskeleton IDA
IDA: 通过直接分析推断
15003631 MGI
located in neuronal cell body IDA
IDA: 通过直接分析推断
23284756 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

tubulin beta-3 chain

betaIII-tubulin

Tubb3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Tubb3 Q9ERD7 Capzb Mus musculus P47757
Anti Bait CoIP
19806181
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-158208 PMMB276 Inhibitor / 否
HY-RS15254 TUBB3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19491 Tubb3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25985 Tubb3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tubb3 NCBI NCBI:10381
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