2. Gene
  3. Tyrp1 - tyrosinase-related protein 1 Gene

Tyrp1 - tyrosinase-related protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: b; isa; Oca3; TRP1; Tyrp; TRP-1; brown

基因 ID: 22178 | 基因类型: protein coding

关于 Tyrp1

功能概要

Enables protein homodimerization activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within several processes, including acetoacetic acid metabolic process; melanocyte differentiation; and melanosome organization. Located in melanosome membrane. Is expressed in several structures, including hip; nervous system; sensory organ; skeleton; and skin. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (Tyrosinase related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Tyrp1 基因产物(3)

mRNA Protein Name
NM_001282014.1 NP_001268943.1 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor
NM_001282015.1 NP_001268944.1 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor
NM_031202.3 NP_112479.1 5,6-dihydroxyindole-2-carboxylic acid oxidase precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
9918801 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9918801 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
9918801 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within acetoacetic acid metabolic process IMP
IMP: 通过突变表型推断
7665913 MGI
acts upstream of or within melanin metabolic process IMP
IMP: 通过突变表型推断
9548375 MGI
acts upstream of or within melanocyte differentiation IMP
IMP: 通过突变表型推断
2379821 MGI
acts upstream of or within melanosome organization IMP
IMP: 通过突变表型推断
9548375 MGI
acts upstream of or within pigmentation IMP
IMP: 通过突变表型推断
2379821 MGI
involved in positive regulation of melanin biosynthetic process IGI
IGI: 通过遗传相互作用推断
21949658 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in melanosome IDA
IDA: 通过直接分析推断
9918801 MGI
located in melanosome membrane IDA
IDA: 通过直接分析推断
17182842 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

5,6-dihydroxyindole-2-carboxylic acid oxidase

DHICA oxidase

brown locus protein

catalase B

iris stromal atrophy

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99622 Flanvotumab Inhibitor 97.83% Phase 1
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N6069 Raspberry ketone glucoside Activator 99.52% 否
HY-161612 Mycosporine 2 glycine Inhibitor / 否
HY-RS15310 TYRP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18847 Tyrp1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25339 Tyrp1 Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990149 Anti-Mouse/Human TYRP1 Antibody (TA99) Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tyrp1 NCBI NCBI:7306
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