1. Gene
  2. Ube2i - ubiquitin-conjugating enzyme E2I Gene

Ube2i - ubiquitin-conjugating enzyme E2I Gene

种属: Mus musculus

同用名: UBC9; Ubce9; Ubce2i; 5830467E05Rik

基因 ID: 22196 | 基因类型: protein coding

关于 Ube2i

功能概要

Enables HLH domain binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within positive regulation of I-kappaB kinase/NF-kappaB signaling. Located in nuclear body. Is expressed in several structures, including early embryo; forebrain; forelimb bud; limb; and oocyte. Orthologous to human UBE2I (Ubiquitin Conjugating Enzyme E2 I). [provided by Alliance of Genome Resources, Apr 2022]

Ube2i 基因产物(4)

mRNA Protein Name
NM_001177609.1 NP_001171080.1 SUMO-conjugating enzyme UBC9
NM_001177610.1 NP_001171081.1 SUMO-conjugating enzyme UBC9
NM_001357694.1 NP_001344623.1 SUMO-conjugating enzyme UBC9
NM_011665.4 NP_035795.1 SUMO-conjugating enzyme UBC9
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables HLH domain binding IPI
IPI: 通过物理相互作用推断
9409784 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
9223278 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in modulation of chemical synaptic transmission IDA
IDA: 通过直接分析推断
25448527 MGI
involved in modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
25448527 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16127449 MGI
involved in nuclear export EXP
EXP: 通过实验结果推断
27160050 MGI
acts upstream of or within positive regulation of canonical NF-kappaB signal transduction IDA
IDA: 通过直接分析推断
9223278 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SUMO ligase complex IDA
IDA: 通过直接分析推断
22207709 MGI
is active in Schaffer collateral - CA1 synapse IDA
IDA: 通过直接分析推断
25448527 MGI
is active in Schaffer collateral - CA1 synapse IMP
IMP: 通过突变表型推断
25448527 MGI
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
31749687 MGI
located in nuclear body IDA
IDA: 通过直接分析推断
18681895 MGI
is active in postsynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
is active in presynaptic cytosol IDA
IDA: 通过直接分析推断
31749687 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

SUMO-conjugating enzyme UBC9

RING-type E3 SUMO transferase UBC9

SUMO-protein ligase

ubiquitin carrier protein 9

ubiquitin carrier protein I

ubiquitin-protein ligase I

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ube2i NCBI NCBI:7329