2. Gene
  3. Usp9x - ubiquitin specific peptidase 9, X chromosome Gene

Usp9x - ubiquitin specific peptidase 9, X chromosome Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fafl; Dffrx; FAF-X; 5730589N07Rik

基因 ID: 22284 | 基因类型: protein coding

关于 Usp9x

功能概要

Enables Deubiquitinase activity and ubiquitin protein Ligase binding activity. Involved in neuron migration and protein deubiquitination involved in ubiquitin-dependent protein catabolic process. Acts upstream of or within several processes, including cellular response to transforming growth factor beta stimulus; in utero embryonic development; and nervous system development. Located in apical part of cell and cytoplasm. Is expressed in several structures, including central nervous system; eye; limb interdigital region; lung; and reproductive system. Human ortholog(s) of this gene implicated in female-restricted syndromic X-linked intellectual disability 99 and non-syndromic X-linked intellectual disability 99. Orthologous to human USP9X (ubiquitin specific peptidase 9 X-linked). [provided by Alliance of Genome Resources, Apr 2022]

Usp9x 基因产物(4)

mRNA Protein Name
NM_001408717.1 NP_001395646.1 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 1
NM_001408718.1 NP_001395647.1 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 2
NM_001408719.1 NP_001395648.1 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 2
NM_009481.3 NP_033507.2 probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cysteine-type deubiquitinase activity IDA
IDA: 通过直接分析推断
12895410 MGI
enables cysteine-type endopeptidase activity IDA
IDA: 通过直接分析推断
30951545 MGI
enables deubiquitinase activity IDA
IDA: 通过直接分析推断
18410486 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
17500595 MGI
enables ubiquitin protein ligase binding IPI
IPI: 通过物理相互作用推断
18410486 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within axon extension IMP
IMP: 通过突变表型推断
23861879 MGI
involved in axon extension IMP
IMP: 通过突变表型推断
24607389 MGI
acts upstream of or within cellular response to transforming growth factor beta stimulus IMP
IMP: 通过突变表型推断
23861879 MGI
acts upstream of or within cerebellar cortex structural organization IMP
IMP: 通过突变表型推断
23861879 MGI
acts upstream of or within hippocampus development IMP
IMP: 通过突变表型推断
23861879 MGI
acts upstream of or within in utero embryonic development IGI
IGI: 通过遗传相互作用推断
23861879 MGI
involved in neuron migration IMP
IMP: 通过突变表型推断
24607389 MGI
acts upstream of or within neuron projection extension IGI
IGI: 通过遗传相互作用推断
23861879 MGI
acts upstream of or within post-embryonic development IMP
IMP: 通过突变表型推断
23861879 MGI
involved in protein deubiquitination IMP
IMP: 通过突变表型推断
18410486 MGI
involved in protein deubiquitination involved in ubiquitin-dependent protein catabolic process IMP
IMP: 通过突变表型推断
29626158 MGI
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
31813652 MGI
involved in regulation of postsynapse assembly IEP
IEP: 通过表达模式推断
31813652 MGI
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
31813652 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical part of cell IDA
IDA: 通过直接分析推断
10704870 MGI
located in cytoplasm IDA
IDA: 通过直接分析推断
15509704 MGI
is active in postsynapse IDA
IDA: 通过直接分析推断
31813652 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

probable ubiquitin carboxyl-terminal hydrolase FAF-X

deubiquitinating enzyme FAF-X

fat facets homolog

fat facets protein-related, X-linked

fats facets protein related, X

ubiquitin carboxyl-terminal hydrolase FAM

ubiquitin thioesterase FAF-X

ubiquitin thiolesterase FAF-X

ubiquitin-specific protease 9,

相关产品

Pre-clinical Phase
生物活性分子 (9)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-13264 Degrasyn 99.70% 否
HY-111408 EOAI3402143 Inhibitor 98.11% 否
HY-145967 FT709 Inhibitor 99.81% 否
HY-149230 USP28-IN-4 Inhibitor 99.35% 否
HY-149229 USP28-IN-3 Inhibitor 98.26% 否
HY-149228 USP28-IN-2 Inhibitor / 否
HY-RS15570 USP9X Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16960 Usp9x Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23403 Usp9x Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Usp9x NCBI NCBI:8239
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