2. Gene
  3. Vdac1 - voltage-dependent anion channel 1 Gene

Vdac1 - voltage-dependent anion channel 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Vdac5; mVDAC1; mVDAC5

基因 ID: 22333 | 基因类型: protein coding

关于 Vdac1

功能概要

This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Multiple pseudogenes of this gene are found on chromosomes 1, 2, 3, 6, 8, 9, and X. [provided by RefSeq, Sep 2015]

Vdac1 基因产物(6)

mRNA Protein Name
NM_001362693.2 NP_001349622.1 voltage-dependent anion-selective channel protein 1 isoform 1
NM_001400986.1 NP_001387915.1 voltage-dependent anion-selective channel protein 1 isoform 3
NM_001400987.1 NP_001387916.1 voltage-dependent anion-selective channel protein 1 isoform 4
NM_001400988.1 NP_001387917.1 voltage-dependent anion-selective channel protein 1 isoform 2
NM_001400989.1 NP_001387918.1 voltage-dependent anion-selective channel protein 1 isoform 2
NM_011694.7 NP_035824.1 voltage-dependent anion-selective channel protein 1 isoform 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oxysterol binding IMP
IMP: 通过突变表型推断
34799735 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22079573 MGI
enables voltage-gated monoatomic anion channel activity IDA
IDA: 通过直接分析推断
18988731 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within behavioral fear response IMP
IMP: 通过突变表型推断
11907043 MGI
acts upstream of or within chemical synaptic transmission IMP
IMP: 通过突变表型推断
11907043 MGI
acts upstream of or within learning IMP
IMP: 通过突变表型推断
11907043 MGI
involved in negative regulation of reactive oxygen species metabolic process IMP
IMP: 通过突变表型推断
25470454 MGI
acts upstream of or within neuron-neuron synaptic transmission IMP
IMP: 通过突变表型推断
11907043 MGI
involved in regulation of mitophagy IMP
IMP: 通过突变表型推断
25470454 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
18988731 MGI
located in mitochondrion IDA
IDA: 通过直接分析推断
17376863 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

voltage-dependent anion-selective channel protein 1

outer mitochondrial membrane protein porin 1

plasmalemmal porin

voltage-dependent anion-selective channel protein 5

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-D0086 DIDS sodium salt Inhibitor 99.13% 否
HY-129122 VBIT-4 Inhibitor 99.46% 否
HY-108937 NSC 15364 Inhibitor 99.67% 否
HY-135885 VBIT-12 Inhibitor 98.87% 否
HY-111217 AKOS-22 Inhibitor 99.23% 否
HY-RS15629 VDAC1 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-121693 DIDS Inhibitor / 否
HY-135571 VBIT-3 Inhibitor / 否
HY-161027 DHP-B Inducer / 否
HY-176745 SW016789 Inducer / 否
HY-RS16872 Vdac1 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23313 Vdac1 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vdac1 NCBI NCBI:7416
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