1. Gene
  2. Vdac2 - voltage-dependent anion channel 2 Gene

Vdac2 - voltage-dependent anion channel 2 Gene

种属: Mus musculus

同用名: Vdac6; mVDAC2; mVDAC6

基因 ID: 22334 | 基因类型: protein coding

关于 Vdac2

功能概要

Predicted to enable several functions, including Cholesterol binding activity; phosphatidylcholine binding activity; and voltage-gated anion channel activity. Involved in negative regulation of intrinsic apoptotic signaling pathway and negative regulation of protein polymerization. Located in mitochondrial inner membrane and myelin sheath. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human VDAC2 (voltage dependent anion channel 2). [provided by Alliance of Genome Resources, Apr 2022]

Vdac2 基因产物(1)

mRNA Protein Name
NM_011695.2 NP_035825.1 voltage-dependent anion-selective channel protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables oxysterol binding IMP
IMP: 通过突变表型推断
34799735 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
12881569 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
12881569 MGI
involved in negative regulation of protein polymerization IMP
IMP: 通过突变表型推断
12881569 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IMP
IMP: 通过突变表型推断
22561200 MGI
located in sperm midpiece IDA
IDA: 通过直接分析推断
33087875 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

voltage-dependent anion-selective channel protein 2

VDAC-2

VDAC-6

outer mitochondrial membrane protein porin 2

voltage-dependent anion-selective channel protein 6

Vdac2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Vdac2 Q60930 Bak1 Mus musculus O08734 12881569
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Vdac2 NCBI NCBI:7417