2. Gene
  3. Zbtb7b - zinc finger and BTB domain containing 7B Gene

Zbtb7b - zinc finger and BTB domain containing 7B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Thpok; Zfp67; c-Krox

基因 ID: 22724 | 基因类型: protein coding

关于 Zbtb7b

功能概要

Enables several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of signal transduction; and regulation of alpha-beta T cell activation. Acts upstream of or within regulation of alpha-beta T cell differentiation and regulation of gene expression. Located in nucleus. Is expressed in several structures, including alimentary system; forebrain; genitourinary system; sensory organ; and skin. Orthologous to human ZBTB7B (zinc finger and BTB domain containing 7B). [provided by Alliance of Genome Resources, Apr 2022]

Zbtb7b 基因产物(8)

mRNA Protein Name
NM_001355206.2 NP_001342135.2 zinc finger and BTB domain-containing protein 7B
NM_001355211.2 NP_001342140.1 zinc finger and BTB domain-containing protein 7B
NM_001355212.2 NP_001342141.1 zinc finger and BTB domain-containing protein 7B
NM_001410678.1 NP_001397607.1 zinc finger and BTB domain-containing protein 7B
NM_001410679.1 NP_001397608.1 zinc finger and BTB domain-containing protein 7B
NM_001410680.1 NP_001397609.1 zinc finger and BTB domain-containing protein 7B
NM_001410681.1 NP_001397610.1 zinc finger and BTB domain-containing protein 7B
NM_009565.6 NP_033591.2 zinc finger and BTB domain-containing protein 7B
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables DNA binding IDA
IDA: 通过直接分析推断
7937772 MGI
enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
IDA: 通过直接分析推断
7937772 MGI
enables DNA-binding transcription factor activity IDA
IDA: 通过直接分析推断
8702912 MGI
enables DNA-binding transcription repressor activity IMP
IMP: 通过突变表型推断
22730529 MGI
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
7937772 MGI
enables cis-regulatory region sequence-specific DNA binding IDA
IDA: 通过直接分析推断
8702912 MGI
enables histone deacetylase binding IPI
IPI: 通过物理相互作用推断
22730529 MGI
enables identical protein binding IDA
IDA: 通过直接分析推断
8702912 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15102471 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
22730529 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in NK T cell differentiation IMP
IMP: 通过突变表型推断
23105140 MGI
involved in adaptive thermogenesis IMP
IMP: 通过突变表型推断
28784777 MGI
involved in lactation IMP
IMP: 通过突变表型推断
29420538 MGI
involved in negative regulation of CD8-positive, alpha-beta T cell differentiation IMP
IMP: 通过突变表型推断
22730529 MGI
involved in negative regulation of NK T cell proliferation IMP
IMP: 通过突变表型推断
23105140 MGI
acts upstream of or within negative regulation of T-helper 17 cell differentiation IMP
IMP: 通过突变表型推断
23034280 MGI
acts upstream of or within negative regulation of gene expression IDA
IDA: 通过直接分析推断
23034280 MGI
involved in negative regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
22730529 MGI
involved in positive regulation of CD4-positive, alpha-beta T cell differentiation IMP
IMP: 通过突变表型推断
24880459 MGI
involved in positive regulation of SREBP signaling pathway IMP
IMP: 通过突变表型推断
29420538 MGI
involved in positive regulation of brown fat cell differentiation IMP
IMP: 通过突变表型推断
28784777 MGI
involved in positive regulation of cold-induced thermogenesis IMP
IMP: 通过突变表型推断
28784777 MGI
acts upstream of or within positive regulation of gene expression IDA
IDA: 通过直接分析推断
21357543 MGI
involved in positive regulation of gene expression IDA
IDA: 通过直接分析推断
24880459 MGI
involved in positive regulation of insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
29420538 MGI
involved in positive regulation of interleukin-17 production IMP
IMP: 通过突变表型推断
23105140 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
7937772 MGI
acts upstream of or within regulation of CD8-positive, alpha-beta T cell differentiation IMP
IMP: 通过突变表型推断
18776904 MGI
acts upstream of or within regulation of T-helper cell differentiation IMP
IMP: 通过突变表型推断
18776904 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
23034280 MGI
involved in response to insulin IMP
IMP: 通过突变表型推断
29420538 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleus IDA
IDA: 通过直接分析推断
29420538 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger and BTB domain-containing protein 7B

T-helper-inducing POZ/Krueppel-like factor

Vzinc finger and BTB domain containing 7B

krueppel-related zinc finger protein cKrox

zinc finger protein 67

zinc finger protein Th-POK

Zbtb7b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Zbtb7b Q64321 Tmpo Mus musculus Q61029
Anti Bait CoIP
22726435
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15980 ZBTB7B Human Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zbtb7b NCBI NCBI:51043
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