2. Gene
  3. Erfe - erythroferrone Gene

Erfe - erythroferrone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Fam132b; myonectin; 4832406C22

基因 ID: 227358 | 基因类型: protein coding

关于 Erfe

功能概要

Enables hormone activity and identical protein binding activity. Involved in cellular iron ion homeostasis. Acts upstream of or within positive regulation of fatty acid transport and regulation of fatty acid metabolic process. Located in extracellular space. Orthologous to human ERFE (erythroferrone). [provided by Alliance of Genome Resources, Apr 2022]

Erfe 基因产物(1)

mRNA Protein Name
NM_173395.2 NP_775571.2 erythroferrone precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables hormone activity IDA
IDA: 通过直接分析推断
24880340 MGI
enables identical protein binding IPI
IPI: 通过物理相互作用推断
22351773 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
30097509 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of establishment of localization in cell IDA
IDA: 通过直接分析推断
22351773 MGI
acts upstream of fatty acid transport IDA
IDA: 通过直接分析推断
22351773 MGI
involved in intracellular iron ion homeostasis IMP
IMP: 通过突变表型推断
24880340 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
30566056 MGI
involved in negative regulation of autophagy IMP
IMP: 通过突变表型推断
24187137 MGI
involved in negative regulation of osteoblast differentiation IMP
IMP: 通过突变表型推断
34002695 MGI
acts upstream of negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
34002695 MGI
acts upstream of or within positive regulation of fatty acid transport IDA
IDA: 通过直接分析推断
22351773 MGI
involved in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
30566056 MGI
acts upstream of or within regulation of fatty acid metabolic process IDA
IDA: 通过直接分析推断
22351773 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular region IDA
IDA: 通过直接分析推断
24880340 MGI
located in extracellular space IDA
IDA: 通过直接分析推断
22351773 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

erythroferrone

complement C1q tumor necrosis factor-related protein 15

family with sequence similarity 132, member B

protein FAM132B

相关产品

Approval
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-P99590A Sotatercept (mIgG2a) Inhibitor 99.71% 否
Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04489 ERFE Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16922 Erfe Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23365 Erfe Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Erfe NCBI NCBI:151176
Canis familiaris Erfe NCBI NCBI:102157118
Macaca fascicularis Erfe NCBI NCBI:102136484
Canis lupus familiaris Erfe NCBI
Susscrofa domestica Erfe NCBI
Rattus norvegicus Erfe NCBI NCBI:681056
Macaca mulatta Erfe NCBI NCBI:706226
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