2. Gene
  3. Elp1 - elongator complex protein 1 Gene

Elp1 - elongator complex protein 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: IKAP; Ikbkap; 6030413P05; 3110040G09Rik

基因 ID: 230233 | 基因类型: protein coding

关于 Elp1

功能概要

Predicted to enable ATP binding activity; protein kinase activity; and tRNA binding activity. Predicted to be involved in I-kappaB phosphorylation and tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation. Predicted to act upstream of or within tRNA processing. Predicted to be located in cytoplasm. Predicted to be part of elongator holoenzyme complex. Predicted to be active in cytosol. Is expressed in several structures, including genitourinary system; liver; lung; spleen; and telencephalon. Used to study Riley-Day syndrome and hemophagocytic lymphohistiocytosis. Human ortholog(s) of this gene implicated in Riley-Day syndrome; asthma; medulloblastoma; and scoliosis. Orthologous to human ELP1 (elongator acetyltransferase complex subunit 1). [provided by Alliance of Genome Resources, Apr 2022]

Elp1 基因产物(1)

mRNA Protein Name
NM_026079.3 NP_080355.2 elongator complex protein 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
28507509 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in tRNA wobble uridine modification IMP
IMP: 通过突变表型推断
23717213 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
23717213 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

elongator complex protein 1

IKK complex-associated protein

IKK-complex-associated protein IKAP

ikappaB kinase complex-associated protein

inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein

Elp1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Elp1 Q7TT37 Gja1 Mus musculus P23242
Anti Bait CoIP
28507509
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-148772 PTC258 Modulator 99.65% 否
HY-147149 BPN-15477 Modulator 99.92% 否
HY-RS04328 ELP1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS07202 KDELR2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22488 Epb41 Mouse Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Elp1 NCBI NCBI:8518
Macaca fascicularis Elp1 NCBI NCBI:102135106
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z