1. Gene
  2. Gckr - glucokinase regulatory protein Gene

Gckr - glucokinase regulatory protein Gene

种属: Mus musculus

同用名: GKRP

基因 ID: 231103 | 基因类型: protein coding

关于 Gckr

功能概要

Predicted to enable several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Involved in positive regulation of Glucokinase activity. Acts upstream of or within cellular glucose homeostasis; negative regulation of Glucokinase activity; and protein import into nucleus. Located in nucleus. Is expressed in diencephalon lateral wall mantle layer; liver left lobe; liver right lobe; midbrain mantle layer; and retina. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (Glucokinase regulator). [provided by Alliance of Genome Resources, Apr 2022]

Gckr 基因产物(2)

mRNA Protein Name
NM_001374741.1 NP_001361670.1 glucokinase regulatory protein isoform 1
NM_144909.2 NP_659158.1 glucokinase regulatory protein isoform 2
蛋白主名 其他名称

glucokinase regulatory protein

glucokinase regulator

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gckr NCBI NCBI:2646