KCNH3 - potassium voltage-gated channel subfamily H member 3 Gene

中文名称：钾电压门控通道亚家族 H 成员 3

种属: Homo sapiens

同用名: BEC1; ELK2; Kv12.2

关于 KCNH3

功能概要

该基因编码的蛋白质是电压门控钾通道 α 亚基，主要在前脑中表达。对小鼠的研究发现，当该基因被敲除时，认知功能会增强。在人类中，编码的蛋白质已被证明能够结合人类免疫缺陷病毒 1 型 (HIV-1) 包膜的糖蛋白 120。已发现该基因的两个转录本变体编码不同的亚型。[RefSeq 提供，2015 年 9 月]

The protein encoded by this gene is a voltage-gated Potassium Channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]