2. Gene
  3. Inpp4b - inositol polyphosphate-4-phosphatase, type II Gene

Inpp4b - inositol polyphosphate-4-phosphatase, type II Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: E130107I17Rik

基因 ID: 234515 | 基因类型: protein coding

关于 Inpp4b

功能概要

Enables lipid binding activity; phosphatidylinositol bisphosphate Phosphatase activity; and phosphatidylinositol trisphosphate Phosphatase activity. Acts upstream of or within several processes, including negative regulation of osteoclast differentiation; regulation of bone remodeling; and regulation of protein kinase B signaling. Located in Golgi apparatus. Is expressed in several structures, including brain; ear; genitourinary system; heart; and musculoskeletal system. Orthologous to human INPP4B (inositol polyphosphate-4-phosphatase type II B). [provided by Alliance of Genome Resources, Apr 2022]

Inpp4b 基因产物(4)

mRNA Protein Name
NM_001024617.3 NP_001019788.1 type II inositol 3,4-bisphosphate 4-phosphatase isoform 2
NM_001297591.1 NP_001284520.1 type II inositol 3,4-bisphosphate 4-phosphatase isoform 1
NM_001297593.1 NP_001284522.1 type II inositol 3,4-bisphosphate 4-phosphatase isoform 3
NM_001297596.1 NP_001284525.1 type II inositol 3,4-bisphosphate 4-phosphatase isoform 4
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipid binding IDA
IDA: 通过直接分析推断
16631325 MGI
enables phosphatidylinositol bisphosphate phosphatase activity IDA
IDA: 通过直接分析推断
21982707 MGI
enables phosphatidylinositol trisphosphate phosphatase activity IDA
IDA: 通过直接分析推断
21982707 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within intracellular calcium ion homeostasis IGI
IGI: 通过遗传相互作用推断
21982707 MGI
acts upstream of or within negative regulation of osteoclast differentiation IGI
IGI: 通过遗传相互作用推断
21982707 MGI
acts upstream of or within negative regulation of osteoclast differentiation IMP
IMP: 通过突变表型推断
21982707 MGI
acts upstream of or within regulation of bone remodeling IMP
IMP: 通过突变表型推断
21982707 MGI
acts upstream of or within regulation of nucleocytoplasmic transport IMP
IMP: 通过突变表型推断
21982707 MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IMP
IMP: 通过突变表型推断
23078915 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

type II inositol 3,4-bisphosphate 4-phosphatase

D-myo-inositol-3,4-bisphosphate 4-phosphohydrolase

phosphatidylinositol-3,4-bisphosphate 4-phosphatase

phosphoinositide 4-phosphatase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06826 INPP4B Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS21875 Inpp4b Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28392 Inpp4b Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Inpp4b NCBI NCBI:8821
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