2. Gene
  3. LILRA4 - leukocyte immunoglobulin like receptor A4 Gene

LILRA4 - leukocyte immunoglobulin like receptor A4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白细胞免疫球蛋白样受体 A4

种属: Homo sapiens

同用名: ILT7; CD85g

基因 ID: 23547 | 基因类型: protein coding

关于 LILRA4

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:54,333,185-54,339,162 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 300 orthologues and 25 paralogues. Biased expression in spleen (RPKM 5.0), lymph node (RPKM 4.4) and 6 other tissues.

功能概要

该基因编码一种免疫球蛋白样细胞表面蛋白，主要在浆细胞样树突状细胞 (PDC) 上表达，并调节这些细胞在免疫反应中的功能。该基因的表达被白细胞介素 3 (IL3) 下调。该基因是位于染色体区域 19q13.4 的一组高度相关的基因之一。[RefSeq 提供，2015 年 1 月]

This gene encodes an immunoglobulin-like cell surface protein that is expressed predominantly on plasmacytoid dendritic cells (PDCs) and modulates the function of these cells in the immune response. Expression of this gene is downregulated by interleukin 3 (IL3). This gene is one of a cluster of highly related genes located at chromosomal region 19q13.4. [provided by RefSeq, Jan 2015]

LILRA4 基因产物(1)

mRNA Protein Name
NM_012276.5 NP_036408.4 leukocyte immunoglobulin-like receptor subfamily A member 4 precursor

LILRA4 蛋白结构

Ig_2

Ig_2: Immunoglobulin domain (28 - 117)

Ig_3

Ig_3: Immunoglobulin domain (122 - 197)

Ig_2

Ig_2: Immunoglobulin domain (227 - 315)

Ig_3

Ig_3: Immunoglobulin domain (323 - 398)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 499 a.a.
蛋白主名 其他名称

leukocyte immunoglobulin-like receptor subfamily A member 4

CD85 antigen-like family member G

重组 LILRA4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P77441 LILRA4/ILT-7/CD85g Protein, Human (HEK293, His) P59901-1 (E24-N446) ≥95%
HY-P78480 LILRA4/ILT-7/CD85g Protein, Human (HEK293, His-Avi) P59901 (E24-N446) ≥95%

关联疾病

疾病名称 别名
Pitt-Hopkins Syndrome

PTHS

Encephalopathy, Severe Epileptic, With Autonomic Dysfunction

Mental Retardation, Syndromal, With Intermittent Hyperventilation

Intellectual Disability, Wide Mouth, Distinctive Facial Features, And Intermittent Hyperventilation Followed By Apnea

Pitt Hopkins Syndrome

Phs

Encephalopathy Severe Epileptic With Autonomic Dysfunction
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07648 LILRA4 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca fascicularis LILRA4 NCBI
Others LILRA4 NCBI
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