1. Gene
  2. Leo1 - Leo1, Paf1/RNA polymerase II complex component Gene

Leo1 - Leo1, Paf1/RNA polymerase II complex component Gene

种属: Mus musculus

同用名: Gm185

基因 ID: 235497 | 基因类型: protein coding

关于 Leo1

功能概要

Predicted to enable RNA polymerase II C-terminal domain phosphoserine binding activity. Involved in endodermal cell fate commitment and stem cell population maintenance. Predicted to be located in centrosome; fibrillar center; and nucleoplasm. Predicted to be part of Cdc73/Paf1 complex. Predicted to be active in nucleus. Is expressed in brain; gonad; heart; and medial-nasal process mesenchyme. Orthologous to human LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component). [provided by Alliance of Genome Resources, Apr 2022]

Leo1 基因产物(1)

mRNA Protein Name
NM_001039522.1 NP_001034611.1 RNA polymerase-associated protein LEO1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to protein binding IPI
IPI: 通过物理相互作用推断
27749823 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
22252316 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in endodermal cell fate commitment IMP
IMP: 通过突变表型推断
19345177 MGI
involved in stem cell population maintenance IMP
IMP: 通过突变表型推断
19345177 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

RNA polymerase-associated protein LEO1

Leo1, Paf1/RNA polymerase II complex component, homolog

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Leo1 NCBI NCBI:123169