2. Gene
  3. GABARAPL1 - GABA type A receptor associated protein like 1 Gene

GABARAPL1 - GABA type A receptor associated protein like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：GABA A 型受体相关蛋白样 1

种属: Homo sapiens

同用名: ATG8; GEC1; APG8L; ATG8B; ATG8L; APG8-LIKE

基因 ID: 23710 | 基因类型: protein coding

关于 GABARAPL1

Cytogenetic location: 12p13.2 Genomic coordinates (GRCh38): 12:10,212,877-10,223,128 (from NCBI)

This gene has 19 transcripts (splice variants), 202 orthologues and 6 paralogues. Broad expression in brain (RPKM 136.2), kidney (RPKM 101.2) and 23 other tissues.

功能概要

启用 Tat 蛋白结合活性和泛素蛋白连接酶结合活性。预计参与自噬体组装；线粒体自噬；和细胞对氮饥饿的反应。位于自噬体中。与线粒体共定位。 [由基因组资源联盟提供，2022 年 4 月]

Enables Tat protein binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in autophagosome assembly; Autophagy of mitochondrion; and cellular response to nitrogen starvation. Located in autophagosome. Colocalizes with mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]

GABARAPL1 基因产物(2)

mRNA Protein Name
NM_001363598.2 NP_001350527.1 gamma-aminobutyric acid receptor-associated protein-like 1 isoform 1
NM_031412.4 NP_113600.1 gamma-aminobutyric acid receptor-associated protein-like 1 isoform 2

GABARAPL1 蛋白结构

Atg8

Atg8: Autophagy protein Atg8 ubiquitin like (14 - 116)

  • 0
  • 100
  • 117 a.a.
蛋白主名 其他名称

gamma-aminobutyric acid receptor-associated protein-like 1

GABA(A) receptor-associated protein-like 1

重组 GABARAPL1 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70913 GABARAPL1/GEC-1 Protein, Human (His) Q9H0R8 (M1-K117) ≥95%

关联疾病

疾病名称 别名
Granulomatous Amebic Encephalitis

Granulomatous Amoebic Encephalitis

Acanthamoeba Encephalitis

Acanthamoeba Granulomatous Encephalitis

Granulomatous Amebic Encephalitis Due To Acanthamoeba
Primary Amebic Meningoencephalitis

Pam

Naegleria Fowleri Infection

Meningoencephalitis Caused By Naegleria Fowleri

Primary Amoebic Meningoencephalitis
Warburg Micro Syndrome 3

WARBM3

Micro Syndrome 3
Warburg Micro Syndrome 2

WARBM2

Micro Syndrome 2
Retinitis Pigmentosa

RP

Rod-Cone Dystrophy

Autosomal Recessive Retinitis Pigmentosa

Non-Syndromic Retinitis Pigmentosa

Pericentral Pigmentary Retinopathy

Pigmentary Retinopathy

Tapetoretinal Degeneration

Rcd

Retinitis Pigmentosa Autosomal Recessive

ARRP

Retinitis Pigmentosa, Autosomal Recessive

Retinitis Pigmentosa 1
Parkinson Disease, Late-Onset

Parkinson Disease

Parkinson'S Disease

PD

PARK

Parkinson Disease, Susceptibility To

Late Onset Parkinson'S Disease

Late Onset Parkinson Disease

Paralysis Agitans

Primary Parkinsonism

Idiopathic Parkinson Disease

Parkinson'S

Parkinson Disease, Late-Onset, Susceptibility To

Parkinson Disease, Age Of Onset, Modifier

Lewy Body Parkinson Disease

Idiopathic Parkinson'S Disease

Pd - [Parkinson Disease]

Parkinson Disease Nos

Parkinson, Nos

Primary Parkinson Disease
Zellweger Syndrome

Cerebrohepatorenal Syndrome

Zellweger Leukodystrophy

Zs

Congenital Iron Overload

Chr

Zws

Severe Pbd-Zsd

Severe Peroxisome Biogenesis Disorder-Zellweger Spectrum Disorder
Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis

ALS

Lou Gehrig Disease

Amyotrophic Lateral Sclerosis Type 1

Charcot Disease

ALS1

Amyotrophic Lateral Sclerosis, Susceptibility To

Fals

Lou Gehrig'S Disease

Mnd

Motor Neuron Disease

Familial Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis 1, Familial

Amyotrophic Lateral Sclerosis 1, Autosomal Dominant

Motor Neuron Disease, Bulbar

Motor Neurone Disease

Amyotrophic Lateral Sclerosis With Dementia

Dementia With Amyotrophic Lateral Sclerosis

Motor Neuron Disease, Amyotrophic Lateral Sclerosis

Sclerosis, Lateral, Amyotrophic

Sclerosis, Lateral, Amyotrophic, Type 1

Amyotrophic Sclerosis

Als - [Amyotrophic Lateral Sclerosis]

Wasting Palsy

Amyotrophic Paralysis

Amyotrophy Lateral Sclerosis

Wasting Paralysis

Spinal Progressive Amyotrophy

Progressive Atrophic Paralysis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05202 GABARAPL1 Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta GABARAPL1 VGNC VGNC:99929
Mus musculus GABARAPL1 MGD MGI:1914980
Canis familiaris GABARAPL1 VGNC VGNC:57447
Rattus norvegicus GABARAPL1 RGD RGD:1596143
Felis catus GABARAPL1 VGNC VGNC:84022
Bos taurus GABARAPL1 VGNC VGNC:56201
Others GABARAPL1 NCBI
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