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  3. Ptprq - protein tyrosine phosphatase, receptor type, Q Gene

Ptprq - protein tyrosine phosphatase, receptor type, Q Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: R-PTP-Q

基因 ID: 237523 | 基因类型: protein coding

关于 Ptprq

功能概要

Predicted to enable protein tyrosine Phosphatase activity. Acts upstream of or within several processes, including detection of mechanical stimulus involved in sensory perception of sound; hematopoietic progenitor cell differentiation; and vestibular receptor cell morphogenesis. Located in stereocilium bundle. Is expressed in cochlea; crista ampullaris; inner ear vestibular component; macula of utricle; and saccule. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 73 and autosomal recessive nonsyndromic deafness 84A. Orthologous to human PTPRQ (protein tyrosine Phosphatase receptor type Q). [provided by Alliance of Genome Resources, Apr 2022]

Ptprq 基因产物(2)

mRNA Protein Name
NM_001081432.2 NP_001074901.1 phosphatidylinositol phosphatase PTPRQ isoform 2 precursor
NM_001370987.1 NP_001357916.1 phosphatidylinositol phosphatase PTPRQ isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
37952086 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within detection of mechanical stimulus involved in sensory perception of sound IMP
IMP: 通过突变表型推断
22357859 MGI
acts upstream of or within hematopoietic progenitor cell differentiation IMP
IMP: 通过突变表型推断
24029230 MGI
acts upstream of or within inner ear morphogenesis IMP
IMP: 通过突变表型推断
14534255 MGI
acts upstream of or within neuromuscular process controlling balance IMP
IMP: 通过突变表型推断
22357859 MGI
acts upstream of or within vestibular receptor cell morphogenesis IMP
IMP: 通过突变表型推断
22357859 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
24285636 MGI
located in stereocilium base IDA
IDA: 通过直接分析推断
24285636 MGI
located in stereocilium bundle IDA
IDA: 通过直接分析推断
22357859 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

phosphatidylinositol phosphatase PTPRQ

phosphotidylinositol phosphatase PTPRQ

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11447 PTPRQ Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS11448 PTPRR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22753 Ptprq Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS29267 Ptprq Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprq NCBI NCBI:374462
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