1. Gene
  2. Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

Mtr - 5-methyltetrahydrofolate-homocysteine methyltransferase Gene

种属: Mus musculus

同用名: MS; D830038K18Rik

基因 ID: 238505 | 基因类型: protein coding

关于 Mtr

功能概要

Enables methionine synthase activity. Acts upstream of or within methionine biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including eye; genitourinary system; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; autistic disorder; hematologic Cancer (multiple); hyperhomocysteinemia; and methylmalonic aciduria and homocystinuria type cblG. Orthologous to human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

Mtr 基因产物(1)

mRNA Protein Name
NM_001081128.3 NP_001074597.1 methionine synthase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables methionine synthase activity IMP
IMP: 通过突变表型推断
11158293 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cobalamin metabolic process IMP
IMP: 通过突变表型推断
11158293 MGI
acts upstream of or within methionine biosynthetic process IMP
IMP: 通过突变表型推断
11158293 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

methionine synthase

cobalamin-dependent methionine synthase

vitamin-B12 dependent methionine synthase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mtr NCBI NCBI:4548