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  3. Map2k5 - mitogen-activated protein kinase kinase 5 Gene

Map2k5 - mitogen-activated protein kinase kinase 5 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：丝裂原活化蛋白激酶激酶 5

种属: Mus musculus

同用名: MEK5; Mapkk5; Prkmk5

基因 ID: 23938 | 基因类型: protein coding

关于 Map2k5

Chromosome 9: 63,071,050-63,285,184 reverse strand.GRCm39:CM001002.3

This gene has 3 transcripts (splice variants), 209 orthologues, 8 paralogues and is associated with 11 phenotypes. Ubiquitous expression in adrenal adult (RPKM 1.5), thymus adult (RPKM 8.4) and 28 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 结合活性和 MAP 激酶激酶活性。在 MAPK 级联和心脏发育的上游或内部起作用。位于主轴。在孕早期表达；卵母细胞;和端脑。与人 MAP2K5（丝裂原活化蛋白激酶激酶 5）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ATP binding activity and MAP kinase kinase activity. Acts upstream of or within MAPK cascade and heart development. Located in spindle. Is expressed in early conceptus; oocyte; and telencephalon. Orthologous to human MAP2K5 (mitogen-activated protein kinase kinase 5). [provided by Alliance of Genome Resources, Apr 2022]

Map2k5 基因产物(4)

mRNA Protein Name
NM_001364493.1 NP_001351422.1 dual specificity mitogen-activated protein kinase kinase 5 isoform 3
NM_001364494.1 NP_001351423.1 dual specificity mitogen-activated protein kinase kinase 5 isoform 4
NM_001364492.1 NP_001351421.1 dual specificity mitogen-activated protein kinase kinase 5 isoform 2
NM_011840.3 NP_035970.1 dual specificity mitogen-activated protein kinase kinase 5 isoform 1

Map2k5 蛋白结构

PB1_Map2k5

PB1_Map2k5: cd06395 (16 - 106)

PKc_MKK5

PKc_MKK5: cd06619 (163 - 441)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 448 a.a.
蛋白主名 其他名称

dual specificity mitogen-activated protein kinase kinase 5

MAP kinase kinase 5

MAPK/ERK kinase 5

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08041 MAP2K5 Human Pre-designed siRNA Set A / 否
HY-RS08042 Map2k5 Mouse Pre-designed siRNA Set A / 否
HY-RS08043 Map2k5 Rat Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map2k5 NCBI NCBI:5607
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