2. Gene
  3. Mgll - monoglyceride lipase Gene

Mgll - monoglyceride lipase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Mgl; Magl

基因 ID: 23945 | 基因类型: protein coding

关于 Mgll

功能概要

This gene encodes a monoglyceride Lipase, which catalyzes the hydrolysis of monoglycerides into fatty acids and glycerol. This enzyme is also thought to hydrolyze the endocannabinoid 2-arachidonoylglycerol. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009]

Mgll 基因产物(9)

mRNA Protein Name
NM_001166249.2 NP_001159721.1 monoglyceride lipase isoform c
NM_001166250.2 NP_001159722.1 monoglyceride lipase isoform d
NM_001166251.2 NP_001159723.1 monoglyceride lipase isoform a
NM_001410533.1 NP_001397462.1 monoglyceride lipase isoform e
NM_001410534.1 NP_001397463.1 monoglyceride lipase isoform f
NM_001410535.1 NP_001397464.1 monoglyceride lipase isoform g
NM_001410536.1 NP_001397465.1 monoglyceride lipase isoform h
NM_001410537.1 NP_001397466.1 monoglyceride lipase isoform i
NM_011844.5 NP_035974.1 monoglyceride lipase isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables monoacylglycerol lipase activity IDA
IDA: 通过直接分析推断
18096503 MGI
enables monoacylglycerol lipase activity IMP
IMP: 通过突变表型推断
20729846 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in acylglycerol catabolic process IDA
IDA: 通过直接分析推断
18096503 MGI
involved in acylglycerol catabolic process IMP
IMP: 通过突变表型推断
20729846 MGI
involved in arachidonate metabolic process IMP
IMP: 通过突变表型推断
20729846 MGI
acts upstream of or within long-term synaptic depression IMP
IMP: 通过突变表型推断
20657592 MGI
involved in monoacylglycerol catabolic process IDA
IDA: 通过直接分析推断
20554061 MGI
acts upstream of or within regulation of axon extension IMP
IMP: 通过突变表型推断
20962221 MGI
involved in regulation of endocannabinoid signaling pathway IMP
IMP: 通过突变表型推断
20729846 MGI
involved in regulation of inflammatory response IMP
IMP: 通过突变表型推断
17700715 MGI
involved in regulation of retrograde trans-synaptic signaling by endocanabinoid IDA
IDA: 通过直接分析推断
22783023 MGI
involved in regulation of retrograde trans-synaptic signaling by endocanabinoid IMP
IMP: 通过突变表型推断
22783023 MGI
involved in regulation of sensory perception of pain IMP
IMP: 通过突变表型推断
17700715 MGI
involved in regulation of signal transduction IMP
IMP: 通过突变表型推断
17700715 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in axon IDA
IDA: 通过直接分析推断
20962221 MGI
is active in cerebellar climbing fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
22783023 MGI
is active in cerebellar climbing fiber to Purkinje cell synapse IMP
IMP: 通过突变表型推断
22783023 MGI
located in cytosol IDA
IDA: 通过直接分析推断
18096503 MGI
located in membrane IDA
IDA: 通过直接分析推断
18096503 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
22783023 MGI
is active in parallel fiber to Purkinje cell synapse IMP
IMP: 通过突变表型推断
22783023 MGI
is active in presynapse IDA
IDA: 通过直接分析推断
22783023 MGI
located in synapse IDA
IDA: 通过直接分析推断
20962221 MGI
located in varicosity IDA
IDA: 通过直接分析推断
20962221 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

monoglyceride lipase

monoacylglycerol lipase

相关产品

Approval
生物活性分子 (1)
目录号 产品名 作用方式
纯度 是否罕见病
HY-18540 KT109 Inhibitor 99.86% 否
Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-124576 ABD-1970 Inhibitor / 否
HY-RS08409 MGLL Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS16868 Mgll Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23309 Mgll Rat Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24917 Clec10a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mgll NCBI NCBI:11343
Rattus norvegicus Mgll NCBI NCBI:29254
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