2. Gene
  3. A4galt - alpha 1,4-galactosyltransferase Gene

A4galt - alpha 1,4-galactosyltransferase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

基因 ID: 239559 | 基因类型: protein coding

关于 A4galt

功能概要

The protein encoded by this gene catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group system. The encoded protein, which is a type II membrane protein found in the Golgi, is also required for the synthesis of the Bacterial verotoxins receptor. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2010]

A4galt 基因产物(3)

mRNA Protein Name
NM_001004150.4 NP_001004150.2 lactosylceramide 4-alpha-galactosyltransferase
NM_001170954.2 NP_001164425.2 lactosylceramide 4-alpha-galactosyltransferase
NM_001370647.1 NP_001357576.1 lactosylceramide 4-alpha-galactosyltransferase
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lactosylceramide 4-alpha-galactosyltransferase activity IDA
IDA: 通过直接分析推断
16476743 MGI
enables lactosylceramide 4-alpha-galactosyltransferase activity IMP
IMP: 通过突变表型推断
16476743 MGI
enables toxic substance binding IMP
IMP: 通过突变表型推断
16476743 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within globoside biosynthetic process IDA
IDA: 通过直接分析推断
16476743 MGI
acts upstream of or within globoside biosynthetic process IMP
IMP: 通过突变表型推断
16476743 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lactosylceramide 4-alpha-galactosyltransferase

Gb3 synthase

Gb3/CD77 synthase

UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

alpha-1,4-N-acetylglucosaminyltransferase

alpha4Gal-T1

globotriaosylceramide synthase

相关产品

Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-E70047 alpha-1,4-Galactosyltransferase (LgtC) / 否
HY-149125 Globotriaosylceramide (porcine RBC) Inhibitor / 否
HY-156208 C2 Adamantanyl galactosylceramide (d18:1/2:0) / 否
HY-RS00013 A4GALT Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18003 A4galt Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24475 A4galt Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens A4galt NCBI NCBI:53947
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