2. Metabolic Enzyme/Protease Neuronal Signaling Epigenetics
  3. Glycosidase Glucosylceramide Synthase (GCS) Glycosyltransferase
  4. C2 Adamantanyl galactosylceramide (d18:1/2:0)

C2 Adamantanyl galactosylceramide (d18:1/2:0)  (Synonyms: AdaGalCer(d18:1/2:0); Admantanyl galactosylceramide (d18:1/2:0); Admantanyl galCer(d18:1/2:0))

目录号: HY-156208
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C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) 是一种具有生物活性的鞘脂。C2 Adamantanyl galactosylceramide (d18:1/2:0) 可在体外刺激葡萄糖脑苷脂酶 (glucocerebrosidase) 的活性。C2 Adamantanyl galactosylceramide (d18:1/2:0) 可抑制微粒体乳糖神经酰胺 ( LacCer) 和葡萄糖脑苷脂 (Gb3) 合酶，并抑制细胞硫苷脂的合成。C2 Adamantanyl galactosylceramide (d18:1/2:0) 可降低正常细胞和溶酶体贮积症 (LSD) 细胞中的葡萄糖神经酰胺 (GlcCer) 水平。C2 Adamantanyl galactosylceramide (d18:1/2:0) 可作为 A4GALT 的底物，并能够降低法布里病细胞中的 Gb3 水平，IC50 为 40 μM。

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C2 Adamantanyl galactosylceramide (d18:1/2:0)

C2 Adamantanyl galactosylceramide (d18:1/2:0) Chemical Structure

CAS No. : 574738-16-2

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C2 Adamantanyl galactosylceramide (d18:1/2:0) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

C2 Adamantanyl galactosylceramide (AdaGalCer) (d18:1/2:0) is a bioactive sphingolipid. C2 Adamantanyl galactosylceramide (d18:1/2:0) stimulates glucocerebrosidase activity in vitro. C2 Adamantanyl galactosylceramide (d18:1/2:0) inhibits microsomal LacCer and Gb3 synthase, and inhibits cell sulfatide synthesis. C2 Adamantanyl galactosylceramide (d18:1/2:0) reduces glucosylceramide (GlcCer) levels in normal and lysosomal storage disease (LSD) cells. C2 Adamantanyl galactosylceramide (d18:1/2:0) acts as a substrate for A4GALT and is able to lower Gb3 levels with an IC50 concentration of 40 μM in fabry disease cells[1][2].

分子量

637.89

Formula

C36H63NO8
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

C2 Adamantanyl galactosylceramide (d18:1/2:0) 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C2 Adamantanyl galactosylceramide (d18:1/2:0)574738-16-2AdaGalCer(d18:1/2:0)Admantanyl galactosylceramide (d18:1/2:0)Admantanyl galCer(d18:1/2:0)GlycosidaseGlucosylceramide Synthase (GCS)GlycosyltransferasesphingolipidLacCerGlcCerfabry diseaseInhibitorinhibitorinhibit

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