2. Gene
  3. Tspo - translocator protein Gene

Tspo - translocator protein Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: MBR; Bzrp; Ptbzr; PTBZR02; RATPTBZR02

基因 ID: 24230 | 基因类型: protein coding

关于 Tspo

功能概要

Enables androgen binding activity and benzodiazepine receptor activity. Involved in several processes, including cellular response to zinc ion; neurogenesis; and positive regulation of cell death. Located in mitochondrial outer membrane. Used to study Cholesterol ester storage disease. Orthologous to human TSPO (translocator protein). [provided by Alliance of Genome Resources, Apr 2022]

Tspo 基因产物(1)

mRNA Protein Name
NM_012515.2 NP_036647.1 translocator protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables androgen binding IDA
IDA: 通过直接分析推断
8918981 RGD
enables benzodiazepine receptor activity IDA
IDA: 通过直接分析推断
2555358 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
17174393 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in adrenal gland development IEP
IEP: 通过表达模式推断
9927316 RGD
involved in behavioral response to pain IMP
IMP: 通过突变表型推断
19555675 RGD
involved in cellular hypotonic response IEP
IEP: 通过表达模式推断
18709649 RGD
involved in cellular response to lipopolysaccharide IEP
IEP: 通过表达模式推断
14678758 RGD
involved in cellular response to zinc ion IEP
IEP: 通过表达模式推断
18709649 RGD
involved in chloride transport IDA
IDA: 通过直接分析推断
14726306 RGD
involved in cholesterol homeostasis IMP
IMP: 通过突变表型推断
29074640 RGD
involved in contact inhibition IDA
IDA: 通过直接分析推断
18190798 RGD
involved in glial cell migration IDA
IDA: 通过直接分析推断
18190798 RGD
involved in monoatomic ion transport IDA
IDA: 通过直接分析推断
14726306 RGD
involved in negative regulation of corticosterone secretion IMP
IMP: 通过突变表型推断
29074640 RGD
involved in negative regulation of glial cell proliferation IDA
IDA: 通过直接分析推断
14678758 RGD
involved in negative regulation of nitric oxide biosynthetic process IDA
IDA: 通过直接分析推断
14678758 RGD
involved in negative regulation of tumor necrosis factor production IDA
IDA: 通过直接分析推断
14678758 RGD
involved in peripheral nervous system axon regeneration IEP
IEP: 通过表达模式推断
8977149 RGD
involved in positive regulation of apoptotic process IMP
IMP: 通过突变表型推断
15284300 RGD
involved in positive regulation of calcium ion transport IMP
IMP: 通过突变表型推断
17174393 RGD
involved in positive regulation of glial cell proliferation IDA
IDA: 通过直接分析推断
18190798 RGD
involved in positive regulation of mitochondrial depolarization IDA
IDA: 通过直接分析推断
15183124 RGD
involved in positive regulation of programmed necrotic cell death IMP
IMP: 通过突变表型推断
15284300 RGD
involved in positive regulation of reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
12437594 RGD
involved in regulation of steroid biosynthetic process IMP
IMP: 通过突变表型推断
9974124 RGD
involved in response to acetylcholine IMP
IMP: 通过突变表型推断
29074640 RGD
involved in response to axon injury IEP
IEP: 通过表达模式推断
15255978 RGD
involved in response to manganese ion IEP
IEP: 通过表达模式推断
12946575 RGD
involved in response to pain IEP
IEP: 通过表达模式推断
19555675 RGD
involved in response to progesterone IEP
IEP: 通过表达模式推断
8201845 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
8201845 RGD
involved in response to vitamin B1 IEP
IEP: 通过表达模式推断
10517697 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
17561380 RGD
involved in steroid biosynthetic process IMP
IMP: 通过突变表型推断
9405411 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
19863077 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

translocator protein

Benzodiazepin receptor (peripheral)

PBR

PKBS

benzodiazepine receptor, peripheral

mitochondrial benzodiazepine receptor

peripheral-type benzodiazepine receptor

相关产品

Clinical Phase
生物活性分子 (4)
目录号 产品名 作用方式
纯度 Phase
HY-15527 Emapunil Inhibitor 99.94% Phase 2
HY-111191 ONO-2952 99.51% Phase 2
HY-122607 DPA-714 99.86% Phase 2
HY-141804 ER176 99.77% Phase 2
Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-19567 PK 11195 Inhibitor ≥99.0% 否
HY-124268 4'-Chlorodiazepam Agonist 99.19% 否
HY-148833 MDM2-p53-IN-16 Inhibitor 99.11% 否
HY-150407 TSPO ligand-1 Inducer ≥98.0% 否
HY-153248 PBR28 99.44% 否
HY-400882 Tosylate-DPA-714 97.01% 否
HY-150409 TSPO ligand-2 99.63% 否
HY-169964 TSPO/Carbonic Anhydrase Modulator 1 Modulator / 否
HY-111191A (R)-ONO-2952 99.97% 否
HY-147225 TSPO Ligand-Linker Conjugates 1 Activator / 否
HY-150410 TSPO ligand-3 / 否
HY-RS15177 TSPO Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS15178 TSPO2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W634748 Desalkylgidazepam Agonist / 否
HY-RS16721 Tspo Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS23157 Tspo Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-W782122 Photoclick cholesterol / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tspo NCBI NCBI:706
Mus musculus Tspo NCBI NCBI:12257
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