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DPA-714 

目录号: HY-122607
产品使用指南

DPA-714 是一种高亲和力的移位蛋白 (TSPO) 配体 (Ki=7 nM),DPA-714 的结构中有一个氟原子,允许用氟 -18 进行标记,并可使用正电子发射断层成像进行活体成像。[18F]DPA-714 在各种神经炎症模型和脑肿瘤模型中成功评估炎症的特异性成像。

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DPA-714 Chemical Structure

DPA-714 Chemical Structure

CAS No. : 958233-07-3

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Description

DPA-714 is a high affinity translocator protein (TSPO) ligand (Ki=7 nM), which is designed with a fluorine atom in its structure, allowing labelling with fluorine -18 and in vivo imaging using positron emission tomography. [18F]DPA-714 successfully evaluates for the specific imaging of inflammation in various models of neuroinflammation and in a brain tumor model[1][2].

IC50 & Target

Ki: 7 nM (TSPO)[1]

Molecular Weight

398.47

Formula

C₂₂H₂₇FN₄O₂

CAS No.

958233-07-3

SMILES

O=C(N(CC)CC)CC1=C2N=C(C)C=C(C)N2N=C1C3=CC=C(OCCF)C=C3

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
DPA-714
目录号:
HY-122607
需求量:

DPA-714

Cat. No.: HY-122607