2. Gene
  3. Cad - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Gene

Cad - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24240 | 基因类型: protein coding

关于 Cad

功能概要

Enables several functions, including aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; and dihydroorotase activity. Involved in several processes, including alpha-amino acid metabolic process; animal organ development; and pyrimidine-containing compound biosynthetic process. Located in cytosol; neuronal cell body; and terminal bouton. Part of protein-containing complex. Used to study hepatocellular carcinoma. Biomarker of hepatocellular carcinoma. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 50. Orthologous to human CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase). [provided by Alliance of Genome Resources, Apr 2022]

Cad 基因产物(1)

mRNA Protein Name
NM_001105710.2 NP_001099180.2 CAD protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aspartate carbamoyltransferase activity IDA
IDA: 通过直接分析推断
1148171 RGD
enables carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IDA
IDA: 通过直接分析推断
1148171 RGD
enables dihydroorotase activity IDA
IDA: 通过直接分析推断
1148171 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
26565 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 'de novo' pyrimidine nucleobase biosynthetic process IDA
IDA: 通过直接分析推断
1476792 RGD
involved in UTP biosynthetic process IDA
IDA: 通过直接分析推断
10659854 RGD
involved in animal organ regeneration IEP
IEP: 通过表达模式推断
13671431 RGD
involved in cellular response to epidermal growth factor stimulus IEP
IEP: 通过表达模式推断
10659854 RGD
involved in cellular response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
8548770 RGD
involved in citrulline biosynthetic process IDA
IDA: 通过直接分析推断
7053379 RGD
involved in female pregnancy IEP
IEP: 通过表达模式推断
6020217 RGD
involved in glutamine metabolic process IDA
IDA: 通过直接分析推断
2803258 RGD
involved in glutamine metabolic process IEP
IEP: 通过表达模式推断
2474281 RGD
involved in heart development IEP
IEP: 通过表达模式推断
14160653 RGD
involved in lactation IEP
IEP: 通过表达模式推断
1476792 RGD
involved in liver development IEP
IEP: 通过表达模式推断
14160653 RGD
involved in response to amine IEP
IEP: 通过表达模式推断
2864015 RGD
involved in response to caffeine IEP
IEP: 通过表达模式推断
6149265 RGD
involved in response to cortisol IEP
IEP: 通过表达模式推断
2353918 RGD
involved in response to insulin IDA
IDA: 通过直接分析推断
3311028 RGD
involved in response to starvation IDA
IDA: 通过直接分析推断
3311028 RGD
involved in response to testosterone IEP
IEP: 通过表达模式推断
6030068 RGD
involved in xenobiotic metabolic process IMP
IMP: 通过突变表型推断
18515330 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
1673139 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
1673139 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
26565 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
1673139 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CAD protein

carbamyl phosphatate synthetase 2

相关产品

Pre-clinical Phase
生物活性分子 (16)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-109160 Rimtuzalcap Activator 99.27% 是
HY-139580 Plazinemdor Agonist 96.61% 否
HY-RS16239 Acod1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-123494 BRD0418 Modulator 99.22% 否
HY-128912 Arborinine Inhibitor 99.87% 否
HY-124609 CAD031 99.39% 否
HY-44809A Izilendustat hydrochloride Inhibitor / 否
HY-103406 PNU-177864 / 否
HY-103406A PNU-177864 hydrochloride / 否
HY-RS00172 ACOD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS01818 CAD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03709 DFFB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-128446 CAY10781 Inhibitor / 否
HY-164466 CAD204520 Inhibitor / 否
HY-RS17214 Cad Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23666 Cad Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P991574 MEDI-5884 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cad NCBI NCBI:790
Macaca fascicularis Cad NCBI NCBI:102128048
Mus musculus Cad NCBI NCBI:69719
Susscrofa domestica Cad NCBI
Macaca mulatta Cad NCBI NCBI:699460
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