2. Gene
  3. Cad - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Gene

Cad - carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: Cpad; 2410008J01Rik

基因 ID: 69719 | 基因类型: protein coding

关于 Cad

功能概要

Enables aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; and dihydroorotase activity. Involved in 'de novo' UMP biosynthetic process. Predicted to be located in nuclear matrix and nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 50. Orthologous to human CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase). [provided by Alliance of Genome Resources, Apr 2022]

Cad 基因产物(5)

mRNA Protein Name
NM_001289522.2 NP_001276451.1 CAD protein isoform 2
NM_001289523.2 NP_001276452.1 CAD protein isoform 3
NM_001403399.1 NP_001390328.1 CAD protein isoform 4
NM_001403400.1 NP_001390329.1 CAD protein isoform 5
NM_023525.3 NP_076014.1 CAD protein isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aspartate carbamoyltransferase activity IDA
IDA: 通过直接分析推断
5125237 MGI
enables carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IDA
IDA: 通过直接分析推断
5125237 MGI
enables carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity IMP
IMP: 通过突变表型推断
33771897 MGI
enables dihydroorotase activity IMP
IMP: 通过突变表型推断
33771897 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in 'de novo' UMP biosynthetic process IMP
IMP: 通过突变表型推断
33771897 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

CAD protein

相关产品

Pre-clinical Phase
生物活性分子 (17)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-109160 Rimtuzalcap Activator 99.27% 是
HY-139580 Plazinemdor Agonist 96.61% 否
HY-RS16239 Acod1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-123494 BRD0418 Modulator 99.22% 否
HY-128912 Arborinine Inhibitor 99.87% 否
HY-N1753 3-(4-Hydroxyphenyl)-1-propanol 98.70% 否
HY-124609 CAD031 99.39% 否
HY-RS01818 CAD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-164466 CAD204520 Inhibitor 99.22% 否
HY-44809A Izilendustat hydrochloride Inhibitor / 否
HY-103406 PNU-177864 / 否
HY-103406A PNU-177864 hydrochloride / 否
HY-RS00172 ACOD1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS03709 DFFB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-128446 CAY10781 Inhibitor / 否
HY-RS17214 Cad Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23666 Cad Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99301 Lokivetmab Inhibitor ≥99.0% 否
HY-P991574 MEDI-5884 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cad NCBI NCBI:790
Macaca fascicularis Cad NCBI NCBI:102128048
Susscrofa domestica Cad NCBI
Rattus norvegicus Cad NCBI NCBI:24240
Macaca mulatta Cad NCBI NCBI:699460
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