2. Gene
  3. Chrm2 - cholinergic receptor, muscarinic 2, cardiac Gene

Chrm2 - cholinergic receptor, muscarinic 2, cardiac Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: M2; Chrm-2; AChR-M2

基因 ID: 243764 | 基因类型: protein coding

关于 Chrm2

功能概要

Enables G protein-coupled acetylcholine receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within G protein-coupled acetylcholine receptor signaling pathway. Is active in cholinergic synapse. Is expressed in several structures, including alimentary system; central nervous system; heart; retina; and trigeminal nerve. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2). [provided by Alliance of Genome Resources, Apr 2022]

Chrm2 基因产物(6)

mRNA Protein Name
NM_001411688.1 NP_001398617.1 muscarinic acetylcholine receptor M2
NM_001411690.1 NP_001398619.1 muscarinic acetylcholine receptor M2
NM_001411691.1 NP_001398620.1 muscarinic acetylcholine receptor M2
NM_001411693.1 NP_001398622.1 muscarinic acetylcholine receptor M2
NM_001411695.1 NP_001398624.1 muscarinic acetylcholine receptor M2
NM_203491.4 NP_987076.2 muscarinic acetylcholine receptor M2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled acetylcholine receptor activity IMP
IMP: 通过突变表型推断
9990086 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within G protein-coupled acetylcholine receptor signaling pathway IMP
IMP: 通过突变表型推断
9990086 MGI
involved in presynaptic modulation of chemical synaptic transmission EXP
EXP: 通过实验结果推断
11880500 MGI
involved in presynaptic modulation of chemical synaptic transmission IMP
IMP: 通过突变表型推断
11880500 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
is active in cholinergic synapse EXP
EXP: 通过实验结果推断
11880500 MGI
is active in cholinergic synapse IMP
IMP: 通过突变表型推断
11880500 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

muscarinic acetylcholine receptor M2

AChR M2

muscarinic acetylcholine receptor 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N8728 Aposcopolamine 98.44% 否
HY-RS02661 CHRM2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19417 Chrm2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25908 Chrm2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Chrm2 NCBI NCBI:1129
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