2. Gene
  3. Rgma - repulsive guidance molecule family member A Gene

Rgma - repulsive guidance molecule family member A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: C230063O06

基因 ID: 244058 | 基因类型: protein coding

关于 Rgma

功能概要

Enables coreceptor activity and signaling receptor binding activity. Acts upstream of or within several processes, including nervous system development; positive regulation of GTPase activity; and positive regulation of membrane protein ectodomain proteolysis. Located in cell surface. Is expressed in several structures, including future brain; gut; nervous system; sensory organ; and trunk somite. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human RGMA (repulsive guidance molecule BMP co-receptor a). [provided by Alliance of Genome Resources, Apr 2022]

Rgma 基因产物(1)

mRNA Protein Name
NM_177740.5 NP_808408.2 repulsive guidance molecule A precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables coreceptor activity IGI
IGI: 通过遗传相互作用推断
15975920 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15975920 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
26651291 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within BMP signaling pathway IGI
IGI: 通过遗传相互作用推断
15975920 MGI
acts upstream of membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
26651291 MGI
acts upstream of or within negative regulation of neuron projection development IGI
IGI: 通过遗传相互作用推断
26651291 MGI
acts upstream of or within negative regulation of neuron projection development IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within negative regulation of receptor binding IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
14749425 MGI
acts upstream of or within neuron projection development IMP
IMP: 通过突变表型推断
26651291 MGI
acts upstream of or within positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
26651291 MGI
acts upstream of or within positive regulation of membrane protein ectodomain proteolysis IDA
IDA: 通过直接分析推断
26651291 MGI
acts upstream of or within regulation of BMP signaling pathway IDA
IDA: 通过直接分析推断
17472960 MGI
acts upstream of or within regulation of BMP signaling pathway IMP
IMP: 通过突变表型推断
17472960 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
14749425 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

repulsive guidance molecule A

RGM domain family, member A

相关产品

Clinical Phase
抗体抑制剂 (1)
目录号 产品名 作用方式
纯度 Phase
HY-P99359 Elezanumab Inhibitor 99.91% Phase 2
Pre-clinical Phase
生物活性分子 (6)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-R04609A In Vivo Rgma Rat Pre-designed siRNA Set A-1 Pre-designed Set 98.95% 否
HY-R04609B In Vivo Rgma Rat Pre-designed siRNA Set A-2‍ Pre-designed Set 98.91% 否
HY-R04609C In Vivo Rgma Rat Pre-designed siRNA Set A-3 Pre-designed Set 98.75% 否
HY-RS11894 RGMA Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18785 Rgma Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25274 Rgma Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rgma NCBI NCBI:56963
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