2. Gene
  3. Hspa1a - heat shock protein family A (Hsp70) member 1A Gene

Hspa1a - heat shock protein family A (Hsp70) member 1A Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: HSP72; Hspa1; Hspa1b; HSP70-2; HSP70.1; HSP70.2; Hsp70-1

基因 ID: 24472 | 基因类型: protein coding

关于 Hspa1a

功能概要

Predicted to enable several functions, including ATP binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in several processes, including response to ethanol; response to ischemia; and response to unfolded protein. Located in membrane raft. Human ortholog(s) of this gene implicated in several diseases, including Kawasaki disease; autoimmune disease of musculoskeletal system (multiple); cystic fibrosis; schizophrenia (multiple); and toxic shock syndrome. Orthologous to several human genes including HSPA1B (heat shock protein family A (HSP70) member 1B). [provided by Alliance of Genome Resources, Apr 2022]

Hspa1a 基因产物(1)

mRNA Protein Name
NM_031971.2 NP_114177.2 heat shock 70 kDa protein 1A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables NF-kappaB binding IPI
IPI: 通过物理相互作用推断
16135962 RGD
enables protease binding IPI
IPI: 通过物理相互作用推断
16397188 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9553041 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in defense response IDA
IDA: 通过直接分析推断
11820796 RGD
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
16397188 RGD
involved in negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
IDA: 通过直接分析推断
16397188 RGD
NOT involved in negative regulation of myeloid cell apoptotic process IDA
IDA: 通过直接分析推断
10679071 RGD
involved in negative regulation of vasoconstriction IMP
IMP: 通过突变表型推断
15381648 RGD
involved in positive regulation of T cell mediated cytotoxicity IDA
IDA: 通过直接分析推断
10679071 RGD
involved in response to unfolded protein IMP
IMP: 通过突变表型推断
8271311 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
16609151 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
16609151 RGD
located in membrane raft IDA
IDA: 通过直接分析推断
14499952 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
16135962 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

heat shock 70 kDa protein 1A

HSP70-1/HSP70-2

HSP70.1/2

HSP70.1/HSP70.2

Heat shock 70 kDa protein 1

heat shock 70 kDa protein 1/2

heat shock 70 kDa protein 1A/1B

heat shock 70 kDa protein 1B

heat shock 70 kDa protein 2

heat shock 70kD protein 1A

heat shock protein 70-1

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06424 HSPA1A Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18094 Hspa1a Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24569 Hspa1a Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Hspa1a NCBI NCBI:3303
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