2. Gene
  3. Ldhb - lactate dehydrogenase B Gene

Ldhb - lactate dehydrogenase B Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Ldh2

基因 ID: 24534 | 基因类型: protein coding

关于 Ldhb

功能概要

This gene encodes the B subunit of Lactate Dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have also been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Pseudogenes have been identified on chromosomes X and 9. [provided by RefSeq, Feb 2016]

Ldhb 基因产物(3)

mRNA Protein Name
NM_001316333.1 NP_001303262.1 L-lactate dehydrogenase B chain isoform Ldhbx
NM_001316334.1 NP_001303263.1 L-lactate dehydrogenase B chain isoform Ldhb
NM_012595.2 NP_036727.1 L-lactate dehydrogenase B chain isoform Ldhb
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables L-lactate dehydrogenase activity IDA
IDA: 通过直接分析推断
17447164 RGD
enables NAD binding IDA
IDA: 通过直接分析推断
17447164 RGD
enables identical protein binding IDA
IDA: 通过直接分析推断
7138505 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
17572440 RGD
enables lactate dehydrogenase activity IDA
IDA: 通过直接分析推断
7138505 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
7138505 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in NAD metabolic process IDA
IDA: 通过直接分析推断
17447164 RGD
involved in lactate metabolic process IDA
IDA: 通过直接分析推断
17447164 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

L-lactate dehydrogenase B chain

LDH heart subunit

LDH-B

LDH-H

Lactate dehydrogenease B

相关产品

Pre-clinical Phase
生物活性分子 (12)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-W040118 Galloflavin Inhibitor 99.36% 否
HY-100742A (R)-GNE-140 Inhibitor 99.77% 否
HY-147216 AXKO-0046 Inhibitor 99.77% 否
HY-111108 LDH-IN-1 Inhibitor 99.84% 否
HY-147216A AXKO-0046 dihydrochloride Inhibitor 99.71% 否
HY-124309 NHI-2 99.30% 否
HY-152261 MS6105 99.2% 否
HY-RS07572 LDHB Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-162629 LDHA-IN-7 Inhibitor / 否
HY-176798 NCI-006 / 否
HY-RS16989 Ldhb Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23432 Ldhb Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ldhb NCBI NCBI:3945
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