2. Gene
  3. Pmch - pro-melanin-concentrating hormone Gene

Pmch - pro-melanin-concentrating hormone Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 24659 | 基因类型: protein coding

关于 Pmch

功能概要

Enables type 1 melanin-concentrating hormone receptor binding activity. Involved in several processes, including lactation; modulation of chemical synaptic transmission; and positive regulation of circadian sleep/wake cycle, REM sleep. Located in extracellular space. Biomarker of obesity. Orthologous to human PMCH (pro-melanin concentrating hormone). [provided by Alliance of Genome Resources, Apr 2022]

Pmch 基因产物(1)

mRNA Protein Name
NM_012625.2 NP_036757.2 pro-MCH precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables type 1 melanin-concentrating hormone receptor binding IDA
IDA: 通过直接分析推断
10421367 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in drinking behavior IDA
IDA: 通过直接分析推断
17188345 RGD
involved in feeding behavior IDA
IDA: 通过直接分析推断
12355323 RGD
involved in lactation IEP
IEP: 通过表达模式推断
14962080 RGD
involved in negative regulation of blood pressure IDA
IDA: 通过直接分析推断
17045349 RGD
involved in negative regulation of synaptic transmission, dopaminergic IDA
IDA: 通过直接分析推断
15555641 RGD
involved in positive regulation of circadian sleep/wake cycle, REM sleep IDA
IDA: 通过直接分析推断
12964948 RGD
involved in positive regulation of cytosolic calcium ion concentration IDA
IDA: 通过直接分析推断
10559938 RGD
involved in regulation of heart rate IDA
IDA: 通过直接分析推断
17045349 RGD
involved in regulation of neuronal synaptic plasticity IMP
IMP: 通过突变表型推断
11814630 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
11483240 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

pro-MCH

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10759 PMCH Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS22282 Pmch Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS28805 Pmch Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pmch NCBI NCBI:5367
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