2. Gene
  3. Ptprc - protein tyrosine phosphatase, receptor type, C Gene

Ptprc - protein tyrosine phosphatase, receptor type, C Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Lca; RT7; CD45; L-CA; T200

基因 ID: 24699 | 基因类型: protein coding

关于 Ptprc

功能概要

Enables protein tyrosine Phosphatase activity. Involved in T cell receptor signaling pathway; regulation of gene expression; and response to gamma radiation. Located in cell surface. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in hepatitis C; multiple sclerosis; severe combined immunodeficiency; and severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-positive, Nk cell-positive. Orthologous to human PTPRC (protein tyrosine Phosphatase receptor type C). [provided by Alliance of Genome Resources, Apr 2022]

Ptprc 基因产物(5)

mRNA Protein Name
NM_001109887.2 NP_001103357.1 receptor-type tyrosine-protein phosphatase C isoform 3 precursor
NM_001109888.2 NP_001103358.1 receptor-type tyrosine-protein phosphatase C isoform 5 precursor
NM_001109889.2 NP_001103359.1 receptor-type tyrosine-protein phosphatase C isoform 2 precursor
NM_001109890.2 NP_001103360.1 receptor-type tyrosine-protein phosphatase C isoform 1 precursor
NM_138507.3 NP_612516.2 receptor-type tyrosine-protein phosphatase C isoform 4 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
10814697 RGD
enables protein tyrosine phosphatase activity IGI
IGI: 通过遗传相互作用推断
12496963 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in T cell receptor signaling pathway IGI
IGI: 通过遗传相互作用推断
12496963 RGD
involved in regulation of gene expression IGI
IGI: 通过遗传相互作用推断
12496963 RGD
involved in response to aldosterone IEP
IEP: 通过表达模式推断
29713904 RGD
involved in response to gamma radiation IDA
IDA: 通过直接分析推断
17290791 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
10814697 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
3158393 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

receptor-type tyrosine-protein phosphatase C

T200 glycoprotein

leucocyte common antigen

leukocyte common antigen A

leukocyte common antigen B

protein tyrosine phosphatase, receptor-type, c polypeptide

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11434 PTPRC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18077 Ptprc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24552 Ptprc Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P990495 Anti-PTPRC/CD45 Antibody Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ptprc NCBI NCBI:5788
Mus musculus Ptprc NCBI NCBI:19264
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