1. Gene
  2. Tbxas1 - thromboxane A synthase 1 Gene

Tbxas1 - thromboxane A synthase 1 Gene

种属: Rattus norvegicus

基因 ID: 24886 | 基因类型: protein coding

关于 Tbxas1

功能概要

Predicted to enable heme binding activity; hydroperoxy icosatetraenoate dehydratase activity; and thromboxane-A synthase activity. Involved in several processes, including cellular chloride ion homeostasis; positive regulation of vasoconstriction; and response to ethanol. Predicted to be located in endoplasmic reticulum membrane. Used to study acute necrotizing pancreatitis; artery disease (multiple); brain infarction; glomerulonephritis (multiple); and thrombosis. Biomarker of hydronephrosis. Human ortholog(s) of this gene implicated in Ghosal hematodiaphyseal syndrome; cerebral infarction; and platelet-type bleeding disorder 14. Orthologous to human TBXAS1 (thromboxane A synthase 1). [provided by Alliance of Genome Resources, Apr 2022]

Tbxas1 基因产物(1)

mRNA Protein Name
NM_012687.2 NP_036819.1 thromboxane-A synthase
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular chloride ion homeostasis IMP
IMP: 通过突变表型推断
12023941 RGD
involved in positive regulation of vasoconstriction IMP
IMP: 通过突变表型推断
9370383 RGD
involved in response to ethanol IEP
IEP: 通过表达模式推断
9262373 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
9262373 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

thromboxane-A synthase

TXA synthase

TXS

ThromboxA ane synthase 1

cytochrome P450 5A1

hydroperoxy icosatetraenoate dehydratase

thromboxane A synthase 1, platelet

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tbxas1 NCBI NCBI:6916