2. Gene
  3. Snap25 - synaptosome associated protein 25 Gene

Snap25 - synaptosome associated protein 25 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: SNAP-25B; SNAP-25a

基因 ID: 25012 | 基因类型: protein coding

关于 Snap25

功能概要

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the Other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the Other two. Therefore, this gene product is a presynaptic plasma membrane protein. It is essential for regulated exocytosis in neuronal cells. Alternative transcript variants encoding two different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2012]

Snap25 基因产物(3)

mRNA Protein Name
NM_001270575.1 NP_001257504.1 synaptosomal-associated protein 25 isoform a
NM_001270576.1 NP_001257505.1 synaptosomal-associated protein 25 isoform a
NM_030991.3 NP_112253.1 synaptosomal-associated protein 25 isoform b
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SNARE binding IDA
IDA: 通过直接分析推断
7553862 RGD
enables SNARE binding IPI
IPI: 通过物理相互作用推断
7698987 RGD
enables calcium-dependent protein binding IPI
IPI: 通过物理相互作用推断
12526776 RGD
enables myosin binding IPI
IPI: 通过物理相互作用推断
16030255 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
9759724 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
11152476 RGD
enables syntaxin-1 binding IDA
IDA: 通过直接分析推断
7553862 RGD
enables syntaxin-1 binding IPI
IPI: 通过物理相互作用推断
16030255 RGD
enables transmembrane transporter binding IPI
IPI: 通过物理相互作用推断
19077057 RGD
enables voltage-gated potassium channel activity IDA
IDA: 通过直接分析推断
16478442 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in SNARE complex assembly IMP
IMP: 通过突变表型推断
9671503 RGD
involved in axonogenesis IEP
IEP: 通过表达模式推断
15478103 RGD
involved in calcium ion-regulated exocytosis of neurotransmitter IDA
IDA: 通过直接分析推断
14980208 RGD
involved in endosomal transport IDA
IDA: 通过直接分析推断
16481393 RGD
involved in long-term memory IMP
IMP: 通过突变表型推断
16870134 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
24841827 RGD
involved in positive regulation of hormone secretion IMP
IMP: 通过突变表型推断
15147232 RGD
involved in positive regulation of insulin secretion IEP
IEP: 通过表达模式推断
15042624 RGD
involved in regulation of neuron projection development IMP
IMP: 通过突变表型推断
21986494 RGD
involved in regulation of synapse assembly IEP
IEP: 通过表达模式推断
15478103 RGD
involved in synaptic vesicle exocytosis EXP
EXP: 通过实验结果推断
8103915 RGD
involved in synaptic vesicle exocytosis IDA
IDA: 通过直接分析推断
8103915 RGD
involved in synaptic vesicle exocytosis IEP
IEP: 通过表达模式推断
8103915 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of SNARE complex IDA
IDA: 通过直接分析推断
16030255 RGD
located in actin cytoskeleton IDA
IDA: 通过直接分析推断
10625663 RGD
located in axon IDA
IDA: 通过直接分析推断
10712642 RGD
located in axonal growth cone IDA
IDA: 通过直接分析推断
10712642 RGD
located in endosome IDA
IDA: 通过直接分析推断
16481393 RGD
is active in extrinsic component of presynaptic membrane IDA
IDA: 通过直接分析推断
15983999 RGD
located in filopodium IDA
IDA: 通过直接分析推断
10625663 RGD
is active in glutamatergic synapse EXP
EXP: 通过实验结果推断
8103915 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
8103915 RGD
located in growth cone IDA
IDA: 通过直接分析推断
16598260 RGD
located in lamellipodium IDA
IDA: 通过直接分析推断
10625663 RGD
located in neuron projection IDA
IDA: 通过直接分析推断
16598260 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
10625663 RGD
located in plasma membrane IDA
IDA: 通过直接分析推断
21986494 RGD
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
7698978 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IDA
IDA: 通过直接分析推断
7553862 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a complex IMP
IMP: 通过突变表型推断
9671503 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex IDA
IDA: 通过直接分析推断
7553862 RGD
part of synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex IDA
IDA: 通过直接分析推断
19132534 RGD
part of voltage-gated potassium channel complex IDA
IDA: 通过直接分析推断
16478442 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

synaptosomal-associated protein 25

SNAP-25

SUP

super protein

synaptosomal-associated 25 kDa protein

synaptosomal-associated protein, 25 kDa

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13474 SNAP25 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17856 Snap25 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24325 Snap25 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Snap25 NCBI NCBI:6616
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