1. Gene
  2. Rgn - regucalcin Gene

Rgn - regucalcin Gene

种属: Rattus norvegicus

同用名: Rc; GNL; Reguc

基因 ID: 25106 | 基因类型: protein coding

关于 Rgn

功能概要

Enables calcium ion binding activity and gluconolactonase activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; positive regulation of hydrolase activity; and positive regulation of lipid biosynthetic process. Located in cytosol and nucleus. Used to study familial hyperlipidemia. Biomarker of hepatocellular carcinoma. Orthologous to human RGN (regucalcin). [provided by Alliance of Genome Resources, Apr 2022]

Rgn 基因产物(1)

mRNA Protein Name
NM_031546.2 NP_113734.1 regucalcin
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables calcium ion binding IDA
IDA: 通过直接分析推断
699201 RGD
enables gluconolactonase activity IDA
IDA: 通过直接分析推断
16585534 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in intracellular calcium ion homeostasis IDA
IDA: 通过直接分析推断
16786169 RGD
involved in kidney development IEP
IEP: 通过表达模式推断
8794449 RGD
involved in liver development IEP
IEP: 通过表达模式推断
8794449 RGD
involved in liver regeneration IEP
IEP: 通过表达模式推断
7759556 RGD
involved in negative regulation of DNA biosynthetic process IMP
IMP: 通过突变表型推断
11500948 RGD
involved in negative regulation of DNA catabolic process IDA
IDA: 通过直接分析推断
2001740 RGD
involved in negative regulation of GTPase activity IMP
IMP: 通过突变表型推断
11510494 RGD
involved in negative regulation of RNA biosynthetic process IMP
IMP: 通过突变表型推断
12397604 RGD
involved in negative regulation of apoptotic process IDA
IDA: 通过直接分析推断
15806309 RGD
involved in negative regulation of bone development IDA
IDA: 通过直接分析推断
12239582 RGD
involved in negative regulation of bone development IMP
IMP: 通过突变表型推断
11129957 RGD
involved in negative regulation of calcium-dependent ATPase activity IMP
IMP: 通过突变表型推断
10861851 RGD
involved in negative regulation of cyclic-nucleotide phosphodiesterase activity IDA
IDA: 通过直接分析推断
1656206 RGD
involved in negative regulation of epithelial cell proliferation IDA
IDA: 通过直接分析推断
16142398 RGD
involved in negative regulation of flagellated sperm motility IDA
IDA: 通过直接分析推断
23615721 RGD
involved in negative regulation of macromolecule biosynthetic process IDA
IDA: 通过直接分析推断
2280766 RGD
involved in negative regulation of nitric oxide biosynthetic process IMP
IMP: 通过突变表型推断
12686401 RGD
involved in negative regulation of protein kinase activity IMP
IMP: 通过突变表型推断
11455566 RGD
involved in negative regulation of protein phosphorylation IMP
IMP: 通过突变表型推断
9827702 RGD
involved in positive regulation of ATP-dependent activity IDA
IDA: 通过直接分析推断
16786169 RGD
involved in positive regulation of ATPase-coupled calcium transmembrane transporter activity IDA
IDA: 通过直接分析推断
10797571 RGD
involved in positive regulation of GTPase activity IDA
IDA: 通过直接分析推断
11693188 RGD
involved in positive regulation of fatty acid biosynthetic process IDA
IDA: 通过直接分析推断
16817230 RGD
involved in positive regulation of glucose metabolic process IDA
IDA: 通过直接分析推断
16817230 RGD
involved in positive regulation of phosphatase activity IMP
IMP: 通过突变表型推断
9671264 RGD
involved in positive regulation of proteolysis involved in protein catabolic process IDA
IDA: 通过直接分析推断
1513338 RGD
involved in positive regulation of superoxide dismutase activity IDA
IDA: 通过直接分析推断
15375603 RGD
involved in positive regulation of triglyceride biosynthetic process IDA
IDA: 通过直接分析推断
16817230 RGD
involved in regulation of calcium-mediated signaling IDA
IDA: 通过直接分析推断
16786169 RGD
involved in spermatogenesis IDA
IDA: 通过直接分析推断
23615721 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

regucalcin

SMP-30

gluconolactonase

regucalcin (senescence marker protein-30)

senescence marker protein 30

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Rgn NCBI NCBI:9104