1. Gene
  2. Itga1 - integrin subunit alpha 1 Gene

Itga1 - integrin subunit alpha 1 Gene

种属: Rattus norvegicus

基因 ID: 25118 | 基因类型: protein coding

关于 Itga1

功能概要

Enables Collagen binding activity and signaling receptor binding activity. Involved in several processes, including positive regulation of MAPK cascade; positive regulation of neuron apoptotic process; and vasodilation. Located in several cellular components, including acrosomal vesicle; external side of plasma membrane; and perikaryon. Orthologous to human ITGA1 (Integrin subunit alpha 1). [provided by Alliance of Genome Resources, Apr 2022]

Itga1 基因产物(1)

mRNA Protein Name
NM_030994.2 NP_112256.1 integrin alpha-1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables collagen binding IMP
IMP: 通过突变表型推断
16200076 RGD
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
21969374 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cell chemotaxis IMP
IMP: 通过突变表型推断
16200076 RGD
involved in neuron projection morphogenesis IMP
IMP: 通过突变表型推断
14564503 RGD
involved in positive regulation of MAPK cascade IMP
IMP: 通过突变表型推断
14991844 RGD
involved in positive regulation of neuron apoptotic process IMP
IMP: 通过突变表型推断
14991844 RGD
involved in vasodilation IMP
IMP: 通过突变表型推断
18245559 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in acrosomal vesicle IDA
IDA: 通过直接分析推断
9202984 RGD
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
14991844 RGD
located in perikaryon IDA
IDA: 通过直接分析推断
14991844 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

integrin alpha-1

CD49 antigen-like family member A

VLA-1

laminin and collagen receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Itga1 NCBI NCBI:3672
Mus musculus Itga1 NCBI NCBI:109700