2. Gene
  3. Proc - protein C, inactivator of coagulation factors Va and VIIIa Gene

Proc - protein C, inactivator of coagulation factors Va and VIIIa Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

基因 ID: 25268 | 基因类型: protein coding

关于 Proc

功能概要

Enables oligopeptidase activity and protein self-association. Involved in liver development; negative regulation of blood coagulation; and proteolysis. Located in extracellular space. Human ortholog(s) of this gene implicated in several diseases, including antiphospholipid syndrome; artery disease (multiple); placental abruption; thrombophilia (multiple); and toxic shock syndrome. Orthologous to human PROC (protein C, inactivator of coagulation factors Va and VIIIa). [provided by Alliance of Genome Resources, Apr 2022]

Proc 基因产物(1)

mRNA Protein Name
NM_012803.1 NP_036935.1 vitamin K-dependent protein C precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IDA
IDA: 通过直接分析推断
1440533 RGD
enables oligopeptidase activity IDA
IDA: 通过直接分析推断
1440533 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in liver development IEP
IEP: 通过表达模式推断
7660357 RGD
involved in negative regulation of blood coagulation IDA
IDA: 通过直接分析推断
1440533 RGD
involved in protein catabolic process IDA
IDA: 通过直接分析推断
1440533 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
16522789 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vitamin K-dependent protein C

anticoagulant protein C

autoprothrombin IIA

blood coagulation factor XIV

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11190 PROC Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-E70438 Endoproteinase Pro-C / 否
HY-RS17167 Proc Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23617 Proc Rat Pre-designed siRNA Set A Pre-designed Set / 否
抗体抑制剂 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-P99705 Lifastuzumab vedotin 99.03% 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Proc NCBI NCBI:5624
Macaca fascicularis Proc NCBI NCBI:102136210
Mus musculus Proc NCBI NCBI:19123
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