2. Antibody-drug Conjugate/ADC Related
  3. Antibody-Drug Conjugates (ADCs)
  4. Lifastuzumab vedotin

Lifastuzumab vedotin  (Synonyms: RG-7599; DNIB-0600A; NaPi2b-ADC)

目录号: HY-P99705 纯度: 99.03%
COA 产品使用指南 技术支持

Lifastuzumab vedotin (RG-7599; DNIB0600A) 是一种抗体-药物偶联物 (ADC)，包含人源化 IgG1 抗 NaPi2b 单克隆抗体 (MNIB2126A) 和有效的抗有丝分裂剂单甲基 auristatin E (MMAE; HY-15582)，MMAE 可以通过阻断微管蛋白的聚合来抑制细胞分裂。Lifastuzumab vedotin 具有用于非小细胞肺癌 (NSCLC) 和铂耐药卵巢癌 (PROC) 研究的潜力。

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Lifastuzumab vedotin Chemical Structure

Lifastuzumab vedotin Chemical Structure

CAS No. : 1401812-88-1

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1 mg ￥7600
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Lifastuzumab vedotin 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Lifastuzumab vedotin (RG-7599; DNIB0600A) is an antibody-drug conjugate (ADC) that comprises a humanized IgG1 anti-NaPi2b monoclonal antibody (MNIB2126A) and a potent antimitotic agent, monomethyl auristatin E (MMAE), which inhibits cell division by blocking the polymerization of tubulin. Lifastuzumab vedotin has the potential for non-small cell lung cancer (NSCLC) and platinum-resistant ovarian cancer (PROC) research[1].

Clinical Trial
同用名

RG-7599; DNIB-0600A; NaPi2b-ADC

CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Lifastuzumab vedotin 相关分类

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  • 稀释计算器

The molarity calculator equation

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质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lifastuzumab vedotin1401812-88-1RG-7599 DNIB-0600A NaPi2b-ADCRG7599RG 7599Antibody-Drug Conjugates (ADCs)Antibody-Drug ConjugatesADCIgG1anti-NaPi2bantibodyMNIB2126AantimitoticMMAEcell divisionpolymerizationtubulinnon-small cell lung cancerNSCLCplatinum-resistant ovarian cancerPROCInhibitorinhibitorinhibit

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