1. Gene
  2. Cnp - 2',3'-cyclic nucleotide 3' phosphodiesterase Gene

Cnp - 2',3'-cyclic nucleotide 3' phosphodiesterase Gene

种属: Rattus norvegicus

同用名: CNPF; CNPI; Cnp1; CNPII

基因 ID: 25275 | 基因类型: protein coding

关于 Cnp

功能概要

Enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity and cyclic nucleotide binding activity. Involved in several processes, including aging; regulation of mitochondrial membrane permeability; and response to lipopolysaccharide. Located in several cellular components, including mitochondrial membrane; myelin sheath abaxonal region; and myelin sheath adaxonal region. Used to study carotid stenosis. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 20; multiple sclerosis; and schizophrenia. Orthologous to human CNP (2',3'-cyclic nucleotide 3' phosphodiesterase). [provided by Alliance of Genome Resources, Apr 2022]

Cnp 基因产物(1)

mRNA Protein Name
NM_012809.2 NP_036941.1 2',3'-cyclic-nucleotide 3'-phosphodiesterase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity IDA
IDA: 通过直接分析推断
19357238 RGD
enables cyclic nucleotide binding IDA
IDA: 通过直接分析推断
19357238 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in forebrain development IEP
IEP: 通过表达模式推断
16876328 RGD
involved in regulation of mitochondrial membrane permeability IMP
IMP: 通过突变表型推断
19357238 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
17000237 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell projection IDA
IDA: 通过直接分析推断
16051705 RGD
located in microvillus IDA
IDA: 通过直接分析推断
16876328 RGD
located in mitochondrial inner membrane IDA
IDA: 通过直接分析推断
19357238 RGD
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
19357238 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
17960831 RGD
located in myelin sheath abaxonal region IDA
IDA: 通过直接分析推断
16051705 RGD
located in myelin sheath adaxonal region IDA
IDA: 通过直接分析推断
16051705 RGD
located in perinuclear region of cytoplasm IDA
IDA: 通过直接分析推断
11842207 RGD
located in pseudopodium IDA
IDA: 通过直接分析推断
16876328 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

2',3'-cyclic-nucleotide 3'-phosphodiesterase

CNPase

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cnp NCBI NCBI:1267
Mus musculus Cnp NCBI NCBI:12799