1. Gene
  2. Mfge8 - milk fat globule EGF and factor V/VIII domain containing Gene

Mfge8 - milk fat globule EGF and factor V/VIII domain containing Gene

种属: Rattus norvegicus

同用名: AGS; MFGME8; OAcGD3S; MFGMP-E8

基因 ID: 25277 | 基因类型: protein coding

关于 Mfge8

功能概要

Predicted to enable Integrin binding activity; phosphatidylethanolamine binding activity; and phosphatidylserine binding activity. Involved in positive regulation of cell population proliferation and response to estrogen. Predicted to be located in external side of plasma membrane and extracellular space. Predicted to be extrinsic component of plasma membrane. Human ortholog(s) of this gene implicated in temporal arteritis. Orthologous to human MFGE8 (milk fat globule EGF and factor V/VIII domain containing). [provided by Alliance of Genome Resources, Apr 2022]

Mfge8 基因产物(2)

mRNA Protein Name
NM_001040186.2 NP_001035276.1 lactadherin isoform 1 precursor
NM_012811.3 NP_036943.1 lactadherin isoform 2 precursor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell population proliferation IEP
IEP: 通过表达模式推断
11085522 RGD
involved in response to estrogen IEP
IEP: 通过表达模式推断
12801995 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

lactadherin

MFG-E8

MFGM

O-acetyl GD3 ganglioside synthase

O-acetyl disialoganglioside synthase

O-acetyltransferase Milk fat glolbule membrane protein

O-acetyltransferase milk fat globule membrane protein

SED1

milk fat globule-EGF factor 8 protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mfge8 NCBI NCBI:4240