2. Gene
  3. Ephx1 - epoxide hydrolase 1 Gene

Ephx1 - epoxide hydrolase 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: mEH; MEH8

基因 ID: 25315 | 基因类型: protein coding

关于 Ephx1

功能概要

Enables cis-stilbene-oxide hydrolase activity; enzyme binding activity; and Epoxide Hydrolase activity. Involved in several processes, including cellular response to glucocorticoid stimulus; diol biosynthetic process; and liver development. Located in intracellular membrane-bounded organelle and plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic Cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (Epoxide Hydrolase 1). [provided by Alliance of Genome Resources, Apr 2022]

Ephx1 基因产物(2)

mRNA Protein Name
NM_001034090.3 NP_001029262.1 epoxide hydrolase 1 precursor
NM_012844.3 NP_036976.2 epoxide hydrolase 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables cis-stilbene-oxide hydrolase activity IMP
IMP: 通过突变表型推断
9854022 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
10891369 RGD
enables epoxide hydrolase activity IDA
IDA: 通过直接分析推断
8313504 RGD
enables epoxide hydrolase activity IMP
IMP: 通过突变表型推断
9854022 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to glucocorticoid stimulus IEP
IEP: 通过表达模式推断
2350182 RGD
involved in diol biosynthetic process IDA
IDA: 通过直接分析推断
2507189 RGD
involved in epoxide metabolic process IDA
IDA: 通过直接分析推断
9854022 RGD
involved in liver development IEP
IEP: 通过表达模式推断
2469391 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in intracellular membrane-bounded organelle IDA
IDA: 通过直接分析推断
9245728 RGD
located in membrane IDA
IDA: 通过直接分析推断
9245728 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

epoxide hydrolase 1

epoxide hydratase

epoxide hydrolase 1 (microsomal xenobiotic hydrolase)

epoxide hydrolase 1, microsomal (xenobiotic)

liver microsomal xenobiotic epoxide hydrolase

microsomal epoxide hydrolase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04438 EPHX1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18662 Ephx1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS25148 Ephx1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ephx1 NCBI NCBI:2052
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