2. Gene
  3. Ms4a2 - membrane spanning 4-domains A2 Gene

Ms4a2 - membrane spanning 4-domains A2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: FCIGA; Ms4a1; Fcer1b

基因 ID: 25316 | 基因类型: protein coding

关于 Ms4a2

功能概要

Enables SH2 domain binding activity; phosphoprotein binding activity; and protein kinase binding activity. Contributes to IgE receptor activity. Involved in several processes, including activation of Phospholipase C activity; positive regulation of mast cell degranulation; and protein kinase C-activating G protein-coupled receptor signaling pathway. Located in endosome and membrane raft. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in asthma; atopic dermatitis; and rhinitis. Orthologous to human MS4A2 (membrane spanning 4-domains A2). [provided by Alliance of Genome Resources, Apr 2022]

Ms4a2 基因产物(1)

mRNA Protein Name
NM_012845.1 NP_036977.1 high affinity immunoglobulin epsilon receptor subunit beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables SH2 domain binding IDA
IDA: 通过直接分析推断
8910399 RGD
enables phosphoprotein binding IPI
IPI: 通过物理相互作用推断
8910399 RGD
enables protein kinase binding IPI
IPI: 通过物理相互作用推断
16177098 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of mast cell degranulation IMP
IMP: 通过突变表型推断
16177098 RGD
involved in regulation of release of sequestered calcium ion into cytosol IGI
IGI: 通过遗传相互作用推断
16177098 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endosome IDA
IDA: 通过直接分析推断
11101638 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

high affinity immunoglobulin epsilon receptor subunit beta

IgE Fc receptor subunit beta

Membrane-spanning 4-domains, subfamily A, member 1

beta polypeptide)

fc epsilon receptor I beta-chain

fcERI

membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for

membrane-s

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08697 Ms4a1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08700 MS4A2 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18183 Ms4a2 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24657 Ms4a2 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ms4a2 NCBI NCBI:2206
Macaca fascicularis Ms4a2 NCBI NCBI:102127416
Canis lupus familiaris Ms4a2 NCBI
Mus musculus Ms4a2 NCBI NCBI:14126
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