2. Gene
  3. Alad - aminolevulinate dehydratase Gene

Alad - aminolevulinate dehydratase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: ALADR; aminolevulinatedelta-dehydratase

基因 ID: 25374 | 基因类型: protein coding

关于 Alad

功能概要

Enables porphobilinogen synthase activity and Proteasome core complex binding activity. Involved in several processes, including cellular response to lead ion; response to herbicide; and response to vitamin. Located in cytosol and extracellular space. Used to study anemia and hemochromatosis. Biomarker of acute kidney failure; hypothyroidism; liver cirrhosis; status epilepticus; and visual epilepsy. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Alad 基因产物(1)

mRNA Protein Name
NM_012899.2 NP_037031.1 delta-aminolevulinic acid dehydratase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables porphobilinogen synthase activity IDA
IDA: 通过直接分析推断
19095280 RGD
enables proteasome core complex binding IDA
IDA: 通过直接分析推断
21640720 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to lead ion IEP
IEP: 通过表达模式推断
16566714 RGD
involved in heme biosynthetic process IDA
IDA: 通过直接分析推断
1764448 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
12171438 RGD
involved in response to aluminum ion IEP
IEP: 通过表达模式推断
518129 RGD
involved in response to amino acid IEP
IEP: 通过表达模式推断
8295845 RGD
involved in response to arsenic-containing substance IDA
IDA: 通过直接分析推断
17086449 RGD
involved in response to arsenic-containing substance IEP
IEP: 通过表达模式推断
19966145 RGD
involved in response to cadmium ion IDA
IDA: 通过直接分析推断
7896311 RGD
involved in response to cadmium ion IEP
IEP: 通过表达模式推断
20019094 RGD
involved in response to cobalt ion IEP
IEP: 通过表达模式推断
826600 RGD
involved in response to ethanol IDA
IDA: 通过直接分析推断
2394940 RGD
involved in response to fatty acid IEP
IEP: 通过表达模式推断
20026167 RGD
involved in response to glucocorticoid IEP
IEP: 通过表达模式推断
12596873 RGD
involved in response to herbicide IEP
IEP: 通过表达模式推断
12180188 RGD
involved in response to hormone IEP
IEP: 通过表达模式推断
9468112 RGD
involved in response to hypoxia IEP
IEP: 通过表达模式推断
3697363 RGD
involved in response to ionizing radiation IEP
IEP: 通过表达模式推断
17916974 RGD
involved in response to iron ion IEP
IEP: 通过表达模式推断
14598909 RGD
involved in response to lead ion IEP
IEP: 通过表达模式推断
16597373 RGD
involved in response to lipopolysaccharide IEP
IEP: 通过表达模式推断
19344711 RGD
involved in response to mercury ion IEP
IEP: 通过表达模式推断
17881112 RGD
involved in response to metal ion IDA
IDA: 通过直接分析推断
15302091 RGD
involved in response to metal ion IEP
IEP: 通过表达模式推断
3629603 RGD
involved in response to methylmercury IEP
IEP: 通过表达模式推断
19874286 RGD
involved in response to nutrient IDA
IDA: 通过直接分析推断
2394940 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
8000239 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
19647414 RGD
involved in response to oxidative stress IEP
IEP: 通过表达模式推断
17916976 RGD
involved in response to platinum ion IEP
IEP: 通过表达模式推断
925603 RGD
involved in response to selenium ion IEP
IEP: 通过表达模式推断
15721883 RGD
involved in response to toxic substance IEP
IEP: 通过表达模式推断
20517888 RGD
involved in response to vitamin IEP
IEP: 通过表达模式推断
9559098 RGD
involved in response to vitamin B1 IEP
IEP: 通过表达模式推断
20088549 RGD
involved in response to vitamin E IEP
IEP: 通过表达模式推断
17572058 RGD
involved in response to xenobiotic stimulus IDA
IDA: 通过直接分析推断
8070841 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
19486337 RGD
involved in response to zinc ion IDA
IDA: 通过直接分析推断
3987589 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in extracellular space IDA
IDA: 通过直接分析推断
19111884 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

delta-aminolevulinic acid dehydratase

ALADH

aminolevulinate, delta-, dehydratase

delta - aminolevulinic acid dehydratase

porphobilinogen synthase

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00553 ALAD Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS17104 Alad Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23548 Alad Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Alad NCBI NCBI:210
Macaca fascicularis Alad NCBI NCBI:102130527
Mus musculus Alad NCBI NCBI:17025
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