2. Gene
  3. METAP1D - methionyl aminopeptidase type 1D, mitochondrial Gene

METAP1D - methionyl aminopeptidase type 1D, mitochondrial Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：1D 型甲硫氨酰氨基肽酶，线粒体

种属: Homo sapiens

同用名: MAP1D; MAP 1D; Metap1l; MetAP 1D

基因 ID: 254042 | 基因类型: protein coding

关于 METAP1D

Cytogenetic location: 2q31.1 Genomic coordinates (GRCh38): 2:171,999,953-172,082,430 (from NCBI)

This gene has 7 transcripts (splice variants), 204 orthologues and 7 paralogues. Ubiquitous expression in ovary (RPKM 4.2), endometrium (RPKM 2.3) and 25 other tissues.

功能概要

N-末端甲硫氨酸切除途径是从许多蛋白质中去除 N-末端甲硫氨酸从而促进后续蛋白质修饰的重要过程。在线粒体中，催化该反应的酶是细胞甲硫氨酸氨基肽酶 (MetAps 或 MAP；EC 3.4.11.18) (Serero 等人，2003 [PubMed 14532271]) 。[OMIM 提供，2008 年 3 月]

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases (MetAps, or MAPs; EC 3.4.11.18) (Serero et al., 2003 [PubMed 14532271]).[supplied by OMIM, Mar 2008]

METAP1D 基因产物(3)

mRNA Protein Name
NM_001322278.2 NP_001309207.1 methionine aminopeptidase 1D, mitochondrial isoform 2
NM_001322279.2 NP_001309208.1 methionine aminopeptidase 1D, mitochondrial isoform 2
NM_199227.3 NP_954697.1 methionine aminopeptidase 1D, mitochondrial isoform 1 precursor

METAP1D 蛋白结构

Peptidase_M24

Peptidase_M24: Metallopeptidase family M24 (97 - 321)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
蛋白主名 其他名称

methionine aminopeptidase 1D, mitochondrial

CDS of metAP-3 within PCR fragment

重组 METAP1D 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70862 METAP1D/Methionine aminopeptidase 1D Protein, Human (His) Q6UB28 (R44-A335) ≥95%

关联疾病

疾病名称 别名
Spinocerebellar Ataxia 28

Spinocerebellar Ataxia Type 28

SCA28

Ataxia, Spinocerebellar, Type 28
Perrault Syndrome

Gonadal Dysgenesis, Xx Type, With Deafness

Ovarian Dysgenesis With Sensorineural Deafness

Gonadal Dysgenesis, Xx Type

Gonadal Dysgenesis With Auditory Dysfunction, Autosomal Recessive Inheritance

Gonadal Dysgenesis With Sensorineural Deafness, Autosomal Recessive Inheritance

Xx Gonodal Dysgenesis-Deafness Syndrome

Xx Gonodal Dysgenesis-Hearing Loss Syndrome

Gonadal Dysgenesis Xx Type Deafness
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08349 METAP1D Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus METAP1D RGD RGD:1307413
Mus musculus METAP1D MGD MGI:1913809
Macaca mulatta METAP1D VGNC VGNC:74632
Bos taurus METAP1D VGNC VGNC:31396
Canis familiaris METAP1D VGNC VGNC:53100
Felis catus METAP1D VGNC VGNC:63455
Others METAP1D NCBI
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