1. Gene
  2. Dpysl2 - dihydropyrimidinase-like 2 Gene

Dpysl2 - dihydropyrimidinase-like 2 Gene

种属: Rattus norvegicus

同用名: Crmp2; TOAD-64

基因 ID: 25416 | 基因类型: protein coding

关于 Dpysl2

功能概要

Predicted to enable identical protein binding activity and protein kinase binding activity. Involved in several processes, including central nervous system development; positive regulation of glutamate secretion; and response to amphetamine. Located in several cellular components, including growth cone; myelin sheath; and neuronal cell body. Part of protein-containing complex. Is active in presynapse. Colocalizes with terminal bouton. Biomarker of brain ischemia; hypothyroidism; and status epilepticus. Orthologous to human DPYSL2 (dihydropyrimidinase like 2). [provided by Alliance of Genome Resources, Apr 2022]

Dpysl2 基因产物(1)

mRNA Protein Name
NM_001105717.2 NP_001099187.1 dihydropyrimidinase-related protein 2
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
9375656 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in olfactory bulb development IEP
IEP: 通过表达模式推断
14751288 RGD
involved in positive regulation of glutamate secretion IDA
IDA: 通过直接分析推断
19755421 RGD
involved in regulation of neuron differentiation IMP
IMP: 通过突变表型推断
18218617 RGD
involved in regulation of postsynapse assembly IDA
IDA: 通过直接分析推断
29425794 RGD
involved in regulation of postsynapse assembly IMP
IMP: 通过突变表型推断
29425794 RGD
involved in response to amphetamine IEP
IEP: 通过表达模式推断
20058175 RGD
involved in response to cocaine IEP
IEP: 通过表达模式推断
19457111 RGD
involved in response to xenobiotic stimulus IEP
IEP: 通过表达模式推断
12188101 RGD
involved in spinal cord development IEP
IEP: 通过表达模式推断
8946055 RGD
involved in synaptic vesicle transport IDA
IDA: 通过直接分析推断
19755421 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite IDA
IDA: 通过直接分析推断
19755421 RGD
is active in glutamatergic synapse IDA
IDA: 通过直接分析推断
29425794 RGD
is active in glutamatergic synapse IMP
IMP: 通过突变表型推断
29425794 RGD
located in growth cone IDA
IDA: 通过直接分析推断
7472434 RGD
located in myelin sheath IDA
IDA: 通过直接分析推断
17960831 RGD
located in neuronal cell body IDA
IDA: 通过直接分析推断
19457111 RGD
is active in presynapse IDA
IDA: 通过直接分析推断
19755421 RGD
part of protein-containing complex IDA
IDA: 通过直接分析推断
19755421 RGD
is active in synapse IDA
IDA: 通过直接分析推断
19755421 RGD
is active in synapse IMP
IMP: 通过突变表型推断
19755421 RGD
located in terminal bouton IDA
IDA: 通过直接分析推断
19755421 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

dihydropyrimidinase-related protein 2

CRMP-2

DRP-2

collapsin response mediator protein 2

turned on after division, 64 kDa protein

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Dpysl2 NCBI NCBI:1808