2. Gene
  3. PLA2G4F - phospholipase A2 group IVF Gene

PLA2G4F - phospholipase A2 group IVF Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：磷脂酶 A2 组 IVF

种属: Homo sapiens

同用名: PLA2G4FZ

基因 ID: 255189 | 基因类型: protein coding

关于 PLA2G4F

This gene has 7 transcripts (splice variants), 140 orthologues and 5 paralogues. Biased expression in skin (RPKM 54.3), lung (RPKM 12.6) and 6 other tissues.

功能概要

预测可启用钙离子结合活性；钙依赖性磷脂酶 A2 活性；和钙依赖性磷脂结合活性。预测参与甘油磷脂分解代谢过程。预计在几个过程的上游或内部起作用，包括花生四烯酸分泌；细胞对抗生素的反应；和前列腺素的生物合成过程。预计位于细胞质中。预计在胞质溶胶中有活性；荷叶边膜；和囊泡。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity; calcium-dependent Phospholipase A2 activity; and calcium-dependent phospholipid binding activity. Predicted to be involved in glycerophospholipid catabolic process. Predicted to act upstream of or within several processes, including arachidonic acid secretion; cellular response to antibiotic; and prostaglandin biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol; ruffle membrane; and vesicle. [provided by Alliance of Genome Resources, Apr 2022]

PLA2G4F 基因产物(1)

mRNA Protein Name
NM_213600.4 NP_998765.3 cytosolic phospholipase A2 zeta precursor

PLA2G4F 蛋白结构

C2

C2: C2 domain (46 - 125)

PLA2_B

PLA2_B: Lysophospholipase catalytic domain (359 - 577)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 851 a.a.
蛋白主名 其他名称

cytosolic phospholipase A2 zeta

cPLA2-zeta

关联疾病

疾病名称 别名
Mahvash Disease

Gcgr-Related Hyperglucagonemia

MVAH

Alpha-Cell Hyperplasia With Glucagonemia

Nesidioblastosis, Alpha Cell Hyperplasia, Microglucagonoma, And Nonfunctioning Islet Cell Tumor

Nesidioblastosis Alpha Cell Hyperplasia Microglucagonoma And Nonfunctioning Islet Cell Tumor
Inflammatory Bowel Disease 9

IBD9
Inflammatory Bowel Disease 1

Inflammatory Bowel Disease 1

IBD1

Crohn Disease-Associated Growth Failure

Crohn Disease

Regional Enteritis

Ulcerative Colitis

Crohn Disease-Associated Growth Failure, Susceptibility To

Inflammatory Bowel Disease 1, Crohn Disease

Bowel Disease, Inflammatory, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS10631 PLA2G4F Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus PLA2G4F VGNC VGNC:32962
Felis catus PLA2G4F VGNC VGNC:64202
Canis familiaris PLA2G4F VGNC VGNC:44629
Mus musculus PLA2G4F MGD MGI:2685493
Rattus norvegicus PLA2G4F RGD RGD:1593370
Macaca mulatta PLA2G4F VGNC VGNC:76123
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z