1. Gene
  2. Atp1b1 - ATPase Na+/K+ transporting subunit beta 1 Gene

Atp1b1 - ATPase Na+/K+ transporting subunit beta 1 Gene

种属: Rattus norvegicus

同用名: ATPBS

基因 ID: 25650 | 基因类型: protein coding

关于 Atp1b1

功能概要

Enables P-type sodium:potassium-exchanging transporter activity and protein heterodimerization activity. Involved in potassium ion transport; response to hypoxia; and sodium ion transport. Located in apical plasma membrane; basolateral plasma membrane; and caveola. Part of sodium:potassium-exchanging ATPase complex. Biomarker of sensorineural hearing loss. Human ortholog(s) of this gene implicated in essential hypertension. Orthologous to human ATP1B1 (ATPase Na+/K+ transporting subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Atp1b1 基因产物(1)

mRNA Protein Name
NM_013113.2 NP_037245.2 sodium/potassium-transporting ATPase subunit beta-1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables P-type sodium:potassium-exchanging transporter activity IDA
IDA: 通过直接分析推断
16624992 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
14749213 RGD
enables protein heterodimerization activity IPI
IPI: 通过物理相互作用推断
28787093 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in metal ion transport IDA
IDA: 通过直接分析推断
15327400 RGD
involved in potassium ion transport IDA
IDA: 通过直接分析推断
16624992 RGD
involved in response to hypoxia IDA
IDA: 通过直接分析推断
12573531 RGD
involved in sodium ion transport IDA
IDA: 通过直接分析推断
16624992 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
14749213 RGD
located in basolateral plasma membrane IDA
IDA: 通过直接分析推断
15327400 RGD
located in caveola IDA
IDA: 通过直接分析推断
16624992 RGD
located in membrane IDA
IDA: 通过直接分析推断
28787093 RGD
part of sodium:potassium-exchanging ATPase complex IDA
IDA: 通过直接分析推断
16624992 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sodium/potassium-transporting ATPase subunit beta-1

ATPase, Na+/K+ transporting, beta 1 polypeptide

Na,K-ATPase beta 1 subunit

sodium/potassium-dependent ATPase subunit beta-1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Atp1b1 NCBI NCBI:481
Mus musculus Atp1b1 NCBI NCBI:11931