2. Gene
  3. Gckr - glucokinase regulator Gene

Gckr - glucokinase regulator Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: GKRP; GLRE

基因 ID: 25658 | 基因类型: protein coding

关于 Gckr

功能概要

Enables several functions, including carbohydrate binding activity; enzyme binding activity; and enzyme inhibitor activity. Involved in negative regulation of Glucokinase activity; protein import into nucleus; and response to fructose. Located in cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (Glucokinase regulator). [provided by Alliance of Genome Resources, Apr 2022]

Gckr 基因产物(1)

mRNA Protein Name
NM_013120.2 NP_037252.1 glucokinase regulatory protein
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables carbohydrate binding IDA
IDA: 通过直接分析推断
14627435 RGD
enables carbohydrate binding IMP
IMP: 通过突变表型推断
11756407 RGD
enables enzyme binding IMP
IMP: 通过突变表型推断
11756407 RGD
enables enzyme binding IPI
IPI: 通过物理相互作用推断
16186382 RGD
enables enzyme inhibitor activity IDA
IDA: 通过直接分析推断
11756407 RGD
enables glucose sensor activity IDA
IDA: 通过直接分析推断
14627435 RGD
enables kinase binding IPI
IPI: 通过物理相互作用推断
19807849 RGD
enables kinase inhibitor activity IDA
IDA: 通过直接分析推断
14627435 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
10601273 RGD
enables protein domain specific binding IPI
IPI: 通过物理相互作用推断
16186382 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of hexokinase activity IDA
IDA: 通过直接分析推断
14627435 RGD
involved in protein import into nucleus IDA
IDA: 通过直接分析推断
10601273 RGD
involved in response to fructose IDA
IDA: 通过直接分析推断
14627435 RGD
involved in response to glucose IDA
IDA: 通过直接分析推断
14627435 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
10518020 RGD
located in nucleoplasm IDA
IDA: 通过直接分析推断
10518020 RGD
located in nucleus IDA
IDA: 通过直接分析推断
10601273 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

glucokinase regulatory protein

68-kDa regulatory protein

glucokinase (hexokinase 4) regulator

相关产品

Pre-clinical Phase
生物活性分子 (5)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05332 GCKR Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08083 MAP4K5 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS08084 Map4k5 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS19603 Gckr Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS26099 Gckr Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Gckr NCBI NCBI:2646
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