2. Gene
  3. Zeb1 - zinc finger E-box binding homeobox 1 Gene

Zeb1 - zinc finger E-box binding homeobox 1 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Rattus norvegicus

同用名: Tcf8; Zfhx1a; deltaEF1

基因 ID: 25705 | 基因类型: protein coding

关于 Zeb1

功能概要

Enables chromatin binding activity; double-stranded DNA binding activity; and sequence-specific DNA binding activity. Involved in several processes, including cellular response to transforming growth factor beta stimulus; regulation of transcription by RNA polymerase II; and response to activity. Located in nucleus. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy and posterior polymorphous corneal dystrophy 3. Orthologous to human ZEB1 (zinc finger E-box binding homeobox 1). [provided by Alliance of Genome Resources, Apr 2022]

Zeb1 基因产物(1)

mRNA Protein Name
NM_001308265.2 NP_001295194.1 zinc finger E-box-binding homeobox 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables chromatin binding IDA
IDA: 通过直接分析推断
16824956 RGD
enables double-stranded DNA binding IDA
IDA: 通过直接分析推断
8769566 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
16824956 RGD
enables sequence-specific DNA binding IDA
IDA: 通过直接分析推断
15226419 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to transforming growth factor beta stimulus IEP
IEP: 通过表达模式推断
16824956 RGD
involved in forebrain development IEP
IEP: 通过表达模式推断
11731009 RGD
involved in negative regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11476947 RGD
involved in positive regulation of transcription by RNA polymerase II IMP
IMP: 通过突变表型推断
16824956 RGD
involved in response to activity IEP
IEP: 通过表达模式推断
19366873 RGD
involved in response to nutrient levels IEP
IEP: 通过表达模式推断
19366873 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

zinc finger E-box-binding homeobox 1

TCF-8

transcription factor 8 (represses interleukin 2 expression)

zfhep

zinc finger homeodomain enhancer-binding protein

相关产品

Pre-clinical Phase
生物活性分子 (8)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-N0153 Naringin 99.65% 否
HY-W011338 Benzyl butyl phthalate Activator ≥97.0% 否
HY-131445 RJW100 Activator 99.93% 否
HY-W011338S Benzyl butyl phthalate-d4 98.38% 否
HY-RS16025 ZEB1 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-N0153R Naringin (Standard) / 否
HY-RS16881 Zeb1 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS23323 Zeb1 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Zeb1 NCBI NCBI:6935
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